Bioassay guided fractionation of ethanolic extract of the leaves of Bauhinia racemosa led to the isolation of galactolipid and catechin class of the compounds (1-7) from the most active n-butanol fraction (F4). Among the active galactolipids, 1 emerged as the lead molecule which was active on both forms of lymphatic filarial parasite, Brugia malayi. It was found to be better than the standard drug ivermectin and diethylcarbamazine (DEC) in terms of dose and efficacy.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.ejmech.2012.01.057 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Green Synthesis of Metal-Doped ZnO Nanoparticles Using Lam. Extract and Evaluation of Their Photocatalysis and Biomedical Applications.
ACS Appl Bio Mater
April 2024
Nanotechnology Research and Education Centre, South Ural State University, Chelyabinsk 454080, Russia.
Article Synopsis
- - The study explores the production of ZnO nanoparticles using plant leaf extract and transition metal dopants (Ni, Mn, Co), highlighting the advantages of this green synthesis method over traditional techniques in nanoscience and nanobiotechnology.
- - Structural and functional properties of the nanoparticles were analyzed using various scientific methods, confirming their wurtzite crystal structure and identifying the active functional groups present.
- - The Co-ZnO nanoparticles showed effective photocatalytic degradation of antibiotics (91.09% for tetracycline, 87.97% for ampicillin, and 92.42% for amoxicillin) and demonstrated antimicrobial activities along with cytotoxic and anti-inflammatory properties, making them a promising material for environmental and biomedical applications
Phytochemistry and pharmacological activities of five species of Bauhinia genus: A review.
Fitoterapia
April 2024
Department of Natural Products, National Institute of Pharmaceutical Education and Research, Ahmedabad, Gandhinagar, Gujarat 382355, India. Electronic address:
Genus Bauhinia has been widely used in the treatment of diabetes, malaria, cough, headache, fever, piles, dysentery, flatulence, diarrhoea, ulcer and cardiovascular problems. Among 600 species of this genus, Bauhinia variegata, B. purpurea, B.
View Article and Find Full Text PDFAnimal dietary choices help us understand a species' feeding behaviour and are particularly relevant in conservation management. The aim of this study was to gather knowledge on dietary choices and the foraging behaviour of the Grizzled Giant Squirrel () in Chinnar Wildlife Sanctuary, Southern Western Ghats, Kerala, India. The objectives were in particular to determine the food composition, seasonal fluctuations in food selection and feeding technique.
View Article and Find Full Text PDFEvaluation of Selected Medicinal, Timber and Ornamental Legume Species' Seed Oils as Sources of Bioactive Lipophilic Compounds.
Molecules
May 2023
Institute of Horticulture, Graudu 1, LV-3701 Dobele, Latvia.
Bioactive lipophilic compounds were investigated in 14 leguminous tree species of timber, agroforestry, medicinal or ornamental use but little industrial significance to elucidate their potential in food additive and supplement production. The tree species investigated were: , , , , , , , , , , , , and . The hexane-extracted oils of ripe seeds were chromatographically analysed for their fatty acid composition (GC-MS), tocochromanol (RP-HPLC/FLD), squalene and sterol (GC-FID) content.
View Article and Find Full Text PDFThe complete chloroplast genome of Lam. (Fabaceae): a versatile tropical medicinal plant.
Mitochondrial DNA B Resour
August 2022
Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Mengla, China.
Lam. (1783), a versatile medicinal plant, belongs to the family Fabaceae (subfamily Cercidoideae). In this study, we analyzed the complete chloroplast genome to facilitate its use in genetic research.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!