The organic mol-ecule of the title monohydrate, C(12)H(9)IN(2)O(3)·H(2)O, features a disordered furyl ring with the major component [site occupancy = 0.575 (18)] having the carbonyl O and furyl O atoms syn, and the other conformation having these atoms anti. The mol-ecule is slightly twisted with the dihedral angle between the benzene and furyl rings being 10.3 (6)° (major component). An intra-molecular O-H⋯N(imine) hydrogen bond is formed. In the crystal, the water mol-ecule accepts a hydrogen bond from an amine H atom, and forms two O-H⋯O(carbon-yl) hydrogen bonds, thereby linking three different carbohydrazide mol-ecules. The result is a supra-molecular layer parallel to (001). The closest contacts between layers are of the type I⋯I, at a distance of 3.6986 (6) Å.
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http://dx.doi.org/10.1107/S1600536811055826 | DOI Listing |
J Med Internet Res
January 2025
NOVA National School of Public Health, Public Health Research Centre, Comprehensive Health Research Center, NOVA University Lisbon, Lisbon, Portugal.
Background: Heart failure (HF) is a significant global health problem, affecting approximately 64.34 million people worldwide. The worsening of HF, also known as HF decompensation, is a major factor behind hospitalizations, contributing to substantial health care costs related to this condition.
View Article and Find Full Text PDFJ Fish Dis
January 2025
State Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Yellow Sea Fisheries Research Institute (YSFRI), Chinese Academy of Fishery Sciences (CAFS), Qingdao, Shandong, China.
Hematodinium perezi, a pathogenic dinoflagellate, is one of major epidemiological agents that lead to severe losses of cultured marine crustaceans in China. This study aimed to develop a novel, sensitive and specific detection method qualified for early surveillance and control of the disease caused by H. perezi.
View Article and Find Full Text PDFFront Psychol
January 2025
Department of Neurosciences and Mental Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Therapeutic alliance refers to the collaborative relationship between a therapist and a patient, a concept widely explored in clinical research. It has emerged as a crucial component of effective psychotherapeutic interventions, particularly in the treatment of major depressive disorder (MDD), where its role appears to be multifaceted. In this context, we reviewed the main literature on the role of therapeutic alliance in MDD.
View Article and Find Full Text PDFJ Clin Aesthet Dermatol
January 2025
Ms. Swenson and Dr. Graber are with the Dermatology Institute of Boston in Boston, Massachusetts.
Background: Acne vulgaris (acne) is a common disorder with a complex, multi-faceted pathophysiology. To date, there has not been a single topical treatment that targets all aspects of acne pathophysiology (ie, increased sebum production, presence of , inflammation, and follicular hyperkeratinization). As such, topical treatments need to be utilized in combination to target all four of the major recognized pathophysiologic components in acne lesion formation.
View Article and Find Full Text PDFInt J Cardiol Heart Vasc
February 2025
Department of Cardiology. University Hospital Alvaro Cunqueiro, Vigo, Spain. Galicia Sur Health Research Institute (IIS Galicia Sur). SERGAS-UVIGO.
Introduction And Objectives: Percutaneous left atrial appendage occlusion (LAAO) is a viable option to mitigate bleeding and stroke risks in patients with atrial fibrillation (AF) who are not eligible for oral anticoagulation. Its safety and efficacy in cancer patients remain unclear due to their exclusion from trials. This study aimed to compare short- and long-term LAAO outcomes between cancer and non-cancer patients.
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