James F. Crow and the stochastic theory of population genetics.

Genetics

Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6018, USA.

Published: February 2012

Research in population genetics theory has two main strands. The first is deterministic theory, where random changes in allelic frequencies are ignored and attention focuses on the evolutionary effects of selection and mutation. The second strand, stochastic theory, takes account of these random changes and thus is more complete than deterministic theory. This essay is one in the series of Perspectives and Reviews honoring James F. Crow on the occasion of his 95th birthday. It concerns his contributions to, and involvement with, the stochastic theory of evolutionary population genetics.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276629PMC
http://dx.doi.org/10.1534/genetics.111.135194DOI Listing

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