A computed tomography (CT) and conventional radiography study is reported in a case of HLA-B27 negative ankylosing spondylitis. The value of CT in comparison with conventional radiography in evaluation of anatomic alterations is determined.
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Transpl Immunol
December 2024
Tissue Typing Centre, Clinical Department for Transfusion Medicine and Transplantation Biology, University Hospital Centre Zagreb, Croatia.
This retrospective study analyses the impact HLA heterozygosity, supertypes, and alleles have on incidence of graft versus host disease (GvHD), relapse, overall survival (OS), disease-free survival (DFS) and transplant-related mortality (TRM) after HSCT. The study included patients who underwent HSCT, typed at allele resolution level for HLA-A, -B, -C, -DRB1, -DQB1, and -DPB1 loci. The analysis performed on the entire patient cohort (N = 232) showed that HLA-B07 supertype positive patients demonstrated decreased incidence of relapse, better OS and DFS in comparison to those negative for HLA-B07 supertype.
View Article and Find Full Text PDFClin Rheumatol
December 2024
Immunology and Histocompatibility Department, Hedi Chaker University Hospital, Sfax, Tunisia.
Introduction/objectives: Psoriatic arthritis (PsA) is a chronic inflammatory rheumatism belonging to the spondyloarthritis family. It is a multifactorial disease whose genetic determinism is still poorly understood. It is favored by environmental factors in genetically predisposed individuals.
View Article and Find Full Text PDFZ Rheumatol
December 2024
Klinik für internistische Rheumatologie, Rotes Kreuz Krankenhaus, St.-Pauli-Deich 24, 28199, Bremen, Deutschland.
Clin Rheumatol
November 2024
Department of Rheumatology and Immunology, Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 746 Zhongshan Middle Road, Songjiang District, Shanghai, 201600, China.
Background: Axial spondyloarthritis (ax-SpA) is an autoinflammatory disease affecting multiple organs. While emphasizing the treatment of chronic diseases, it has been found that the prevalence of mental disorders and insomnia in patients is also increasing. We investigated mood status, sleep quality and the health-related quality of life (HRQoL) in these patients.
View Article and Find Full Text PDFFront Immunol
November 2024
Department of Rheumatology and Immunology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
This study aims to report a case of progressive pseudorheumatoid dysplasia (PPRD) with two kinds of cellular communication network factor 6 (CCN6) gene mutation. In this paper, the clinical profile and the process of diagnosis were analyzed, and the related literature was reviewed. A 15-year-old boy, who developed progressive ankle and hip joint pain and enlargement with spine involvement, was diagnosed with PPRD.
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