A selenium analogue of amino-D-luciferin, aminoseleno-D-luciferin, is synthesized and shown to be a competent substrate for the firefly luciferase enzyme. It has a red-shifted bioluminescence emission maximum at 600 nm and is suitable for bioluminescence imaging studies in living subjects.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494413 | PMC |
http://dx.doi.org/10.1002/anie.201105653 | DOI Listing |
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!