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Endoscopic Screening for Laryngotracheal Complications in Children Following Prolonged Mechanical Ventilation Maintained Through Endotracheal Intubation: A Cross-Sectional Pilot Project.
Ann Otol Rhinol Laryngol
December 2024
Department of Otorhinolaryngology & Head-Neck Surgery, Medical College & Hospital, Kolkata; West Bengal, India.
Background: An endoscopic screening program following successful weaning from prolonged mechanical ventilation maintained through endotracheal tube (ET; ) may be justified to assess the upper (laryngotracheal) airway in children who may not always be symptomatic for intubation-related complications.
Objectives: To evaluate effects of prolonged intubation in children through endoscopic screening of the laryngotracheal airway.
Methods: In this cross-sectional pilot project, children (2 months-12 years) successfully extubated following prolonged intubation were selected, irrespective of having symptoms, for a 1-time flexible nasolaryngoscopy at third to sixth month post-extubation (follow-up window).
Maple syrup urine disease diagnosed in a resource-limited setting in an infant in Nepal: a case report.
BMC Pediatr
November 2024
Department of Clinical Biochemistry, Institute of Medicine, Maharajgunj Medical Campus, Tribhuvan University, Maharajgunj, Kathmandu, Nepal.
Background: Maple Syrup Urine Disease (MSUD) is a rare inherited disorder of metabolism, which manifests early in life in classical forms. Recurrent illness and exertion aggravate neurotoxicity. This case highlights MSUD diagnosed in association with COVID-19 complications from Nepal.
View Article and Find Full Text PDFThe evaluation of auditory processing skills and late latencies in children with ventilation tube history.
Int J Pediatr Otorhinolaryngol
November 2024
Department of Otorhinolaryngology- Head and Neck Surgery Ankara Baskent University Hospital, Ankara, Turkey.
Objective: (s): This study aims to evaluate the changes in temporal auditory processing skills in children who underwent bilateral ventilation tube insertion (VTI) due to Otitis Media with Effusion (OME) and the effect of these changes on speech comprehension in noisy environments.
Methods: This is a case-control study. In total, 60 children were included in the study in two groups.
Feasibility of estimating tidal volume from electrocardiograph-derived respiration signal and respiration waveform.
J Crit Care
February 2025
Department of Critical Care Medicine, Seoul National University Hospital, Seoul, Republic of Korea; Department of Anesthesiology and Pain Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea. Electronic address:
Purpose: Estimating tidal volume (V) from electrocardiography (ECG) can be quite useful during deep sedation or spinal anesthesia since it eliminates the need for additional monitoring of ventilation. This study aims to validate and compare V estimation methodologies based on ECG-derived respiration (EDR) using real-world clinical data.
Materials And Methods: We analyzed data from 90 critically ill patients for general analysis and two critically ill patients for constrained analysis.
CAS3D: 3D quantitative morphometry on Second Harmonic Generation image volumes from single skeletal muscle fibers.
Comput Biol Med
August 2024
Institute of Medical Biotechnology, Friedrich-Alexander Universität Erlangen-Nürnberg, Paul-Gordan-Strasse 3, 91052 Erlangn, Germany.
Article Synopsis
- - The CAS3D image processing method combines Fourier and real space algorithms to analyze 3D volumetric images of skeletal muscle fibers, allowing for automated quantification of myofibrillar orientation and mean sarcomere length (SL).
- - The method demonstrated strong reliability, reproducing expected results from ideal data sets, while showing that slight random noise (up to 20%) had a linear effect on CAS3D values without significantly affecting SL and orientation detection.
- - When applied to a rat ICU model studying ventilator-induced diaphragm dysfunction, CAS3D improved the standard deviation of cosine angle sum detection from 0.03 to 0.008 by processing entire 3D images rather than slice-by-slice, enhancing
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