A G-quadruplex-based, label-free, switch-on fluorescence detection method has been developed for the selective detection of ATP in aqueous solution using crystal violet as a G-quadruplex-selective probe. The assay is highly simple and rapid, and does not require the use of fluorescent labeling.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/c2an15999f | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
BSA-Assisted Synthesis of Au Nanoclusters/MnO Nanosheets for Fluorescence "Switch-On" Detection of Alkaline Phosphatase.
Biosensors (Basel)
January 2025
Furong Labratory, Changsha 410083, China.
A fluorescence probe for "switch-on" detection of alkaline phosphatase (ALP) was developed based on Au nanoclusters anchored MnO nanosheets (Au NCs-MnO NSs), which were synthesized using bovine serum albumin (BSA) as template through a simple one-pot approach. In the sensing system, MnO NSs function as both energy acceptors and target identifiers, effectively quenches the fluorescence of Au NCs via fluorescence resonance energy transfer (FRET). The presence of ALP catalyzes the hydrolysis of L-ascorbic acid-2-phosphate (AAP) to ascorbic acid (AA), reducing MnO NSs to Mn and facilitate the fluorescence recovery of Au NCs.
View Article and Find Full Text PDFArchitecture of a novel NIR and switch-on fluorescent chemosensor based on mercapto propanehydrazide-functionalized chromenylium-cyanine for the quantification of mercury(II) in environment and living cells.
Spectrochim Acta A Mol Biomol Spectrosc
March 2025
Istanbul Technical University, Department of Chemistry, 34469 Maslak, Istanbul, Turkey. Electronic address:
A novel probe NIR8 decorated with colorimetric, fluorometric, turn-on, and NIR properties was designed and synthesized using the chromenylium-cyanine platform for sensitive and selective quantification of Hg in real samples. The interaction between the probe and Hg resulted in the opening of the closed spirolactam ring of the chromenylium-cyanine platform, leading to a notable color shift from yellow to green. Concurrently, ratiometric spectral changes at 380 and 725 nm for UV-Vis and signal enhancement at 755 nm for fluorescence were observed.
View Article and Find Full Text PDFMolecular Probe for Specific Recognition of TKX-50: 'Luminescence-ON' Response and its Integration to a Smart Device for Surveillance.
Small
December 2024
Department of Chemical Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur, 741246, India.
Article Synopsis
- - Concerns about the misuse of advanced explosives like TKX-50 emphasize the need for better detection techniques to ensure safety and security.
- - A new polymeric receptor has been developed that exhibits a 'luminescence ON' response when it binds with TKX-50, indicating its potential for efficient explosive detection.
- - This receptor's detection capability can be integrated into a user-friendly IoT device for real-time monitoring of TKX-50, making it a valuable tool for remote surveillance.
Modulating Aggregation and Deaggregation Based on Assembling Strategy to Switch on NIR-II Light-Excited Fluorescence for Self-Reporting Viability of Eliminating Cancer Cell.
Anal Chem
December 2024
School of Chemical and Environmental Engineering, Anhui Polytechnic University, Wuhu 241000, P. R. China.
The fabrication of self-reporting photosensitizers (PSs), enabling real-time evaluation of the extent of elimination of cancer cells, holds significant scientific importance in the photodynamic therapy (PDT) process. To address the intrinsic challenge of the short-wavelength light source, this work proposed an innovative approach of rational design second near-infrared (NIR-II, 1000-1700 nm) light-excited fluorescent PS systems (named , , and , respectively) through modulating aggregation and deaggregation based on assembling strategy. Therein, the suitable interplanar distance of adjacent linked with C-H···π interactions was an idea for relieving compact π···π packing for fluorescent imaging as well as elevating the spin-orbit coupling for reactive oxygen species (ROS) generation.
View Article and Find Full Text PDFCyanuric chloride-modified dendritic SiO nanoparticle for switch-on fluorescence monitoring and dispersive solid-phase extraction of isoquinoline alkaloids.
J Chromatogr A
January 2025
Department of Pharmacy, School of Biomedical and Pharmaceutical Sciences, Shaanxi University of Science & Technology, Xi'an 710021, China. Electronic address:
The determination of isoquinoline alkaloids (IQAs) is crucial for maximizing the pharmacological benefits of Rhizoma coptidis (RC). In this study, the dendritic silica sphere (dSiO) was covalently modified with cyanuric chloride (CNCl) to synthesize a porous dNSiO-CNCl NP. The fluorescence of berberine (Ber), palmatine (Pal), coptisine (Cop), and jatrorrhizine (Jat) was remarkably enhanced by dNSiO-CNCl NP for at least 38-fold, inspiring the accurate determination of the isoquinoline total alkaloids (IQTAs) in RC using fluorometry.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!