Objective: To understand rate of tympanostomy tube placement (TTP) in children with autism spectrum disorder (ASD) and, if different from rate of TTP in the general population, consider reasons underlying the difference.
Methods: Questions pertaining to TTP were asked during caregiver interview. Totally, 2080 children with ASD were characterized through collection of demographic information; medical history; and cognitive, adaptive, and behavioral assessments. Frequencies of TTP in the ASD sample were compared with general population rates according to the most recent literature. Relationships between TTP and factors that may impact the rate of TTP were investigated.
Results: Totally, 15.5% of children with ASD received TTP. The older the age, the higher the rate of TTP, with 17.0% of children aged 13 to 17 years having received TTP. Chi-square results comparing general population TTP rates to the sample indicated significantly higher rates among the ASD population. Logistic regression indicated 2 significant predictors for TTP: otitis media frequency and race. Furthermore, irritability rates in children approached predictive significance (β = 0.015, p < .10).
Conclusions: The authors found that approximately 1 in 6 children with ASD underwent TTP, more than double the rate in the general population. The rate may simply be higher because physicians are swift to perform TTP in children at risk for speech delay. At this time, there exists a lack of data on the outcomes of TTP in children with ASD. More evidence is needed to understand the usefulness of TTP in children with ASD given the high rate of procedures being performed.
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http://dx.doi.org/10.1097/DBP.0b013e31824b9f57 | DOI Listing |
Histol Histopathol
January 2025
Neuropharmacology Division, Department of Pharmacology, ISF College of Pharmacy, Moga, Punjab, India.
Autism spectrum disorder (ASD) is a globally recognized neurodevelopmental condition characterized by repetitive and restrictive behavior, persistent deficits in social interaction and communication, mental disturbances, etc., affecting approximately 1 in 100 children worldwide. A combination of genetic and environmental factors is involved in the etiopathogenesis of the disease, but specific biomarkers have not yet been identified.
View Article and Find Full Text PDFJACC Adv
December 2024
Department of Cardiology, Boston Children's Hospital, Boston, Massachusetts, USA.
Background: Atrial septal defects (ASDs) are a common cause of congenital heart disease worldwide.
Objectives: The purpose of the study was to assess change over time in surgical outcomes for ASD repair and identify patient-level risk factors for adverse postoperative outcomes.
Methods: We analyzed cases of isolated ASD in patients <18 years from 2010 to 2020 from 71 sites participating in the International Quality Improvement Collaborative for Congenital Heart Disease.
Front Child Adolesc Psychiatry
February 2024
Departamento de Psicología Evolutiva y de la Educación, Facultad de Psicología y Logopedia, Universidad de Málaga, Málaga, Spain.
Front Child Adolesc Psychiatry
December 2024
Department of Community and Family Medicine, All India Institute of Medical Sciences, Deoghar (AIIMS Deoghar), Deoghar, India.
Autism spectrum disorder (ASD) is a multifaceted developmental condition characterized by persistent challenges in social communication, restricted interests, and repetitive behaviors. Though there is no cure, early and intensive interventions can significantly improve the quality of life for those affected. The aim of this paper is to examine the complexities of autism spectrum disorder (ASD) from a public health perspective in South East Asian region, highlighting the global rise in prevalence and the compounded challenges posed by the COVID-19 pandemic.
View Article and Find Full Text PDFFront Child Adolesc Psychiatry
November 2024
Department of Psychology, Palo Alto University, Palo Alto, CA, United States.
Introduction: Autism Spectrum Disorder (ASD) is characterized by deficits in social cognition, self-referential processing, and restricted repetitive behaviors. Despite the established clinical symptoms and neurofunctional alterations in ASD, definitive biomarkers for ASD features during neurodevelopment remain unknown. In this study, we aimed to explore if activation in brain regions of the default mode network (DMN), specifically the medial prefrontal cortex (MPC), posterior cingulate cortex (PCC), superior temporal sulcus (STS), inferior frontal gyrus (IFG), angular gyrus (AG), and the temporoparietal junction (TPJ), during resting-state functional magnetic resonance imaging (rs-fMRI) is associated with possible phenotypic features of autism (PPFA) in a large, diverse youth cohort.
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