AI Article Synopsis

  • The study aimed to provide reference values for limb composition, fat-free mass (FFM), and fat mass (FM) in Italian adults aged 20-80, while also examining age-related changes in these parameters.
  • A total of 1571 healthy participants (1240 women and 331 men) were assessed using dual-energy X-ray absorptiometry to measure regional FFM and FM, expressed as a percentage of limb weight.
  • Results indicated that men's FFM decreases with age, while women's FFM remains stable in arms but declines in legs; both genders see an increase in limb FM% as they age, highlighting the importance of understanding these changes for health assessments in Mediterranean populations.

Article Abstract

Background & Aims: To establish reference values for limb composition, fat-free mass (FFM) and fat mass (FM) in Italian adults for gender-specific age brackets 20-80 years old and to assess age-related regional changes in body composition.

Methods: A multicenter, retrospective study was conducted on 1571 healthy subjects, 1240 women and 331 men. Regional FFM and FM were measured by dual-energy X-ray absorptiometry. FM was expressed as % of limb weight.

Results: FFM in men diminished with age in both arms and legs, with reference ranges (25th -75th percentile) of 3.8-4.6 kg and 10.4-12.2 kg, respectively for 20-29 year-olds, and 3.1-3.9 kg and 8.2-10.4 kg for 70-79 year-olds. Women's arm FFM remained stable with aging (reference values 1.7-2.2 kg), decreasing in their legs (6.2-7.2 kg for 20-29 year-olds, 5.5-6.5 kg for 70-79 year-olds). Limb FM% increased with age in both genders: the reference values were 9-15% (arms) and 12-21% (legs) for 20-29 year-old men, and 19-26% and 19-29%, respectively, for 70-79 year-olds; for women's arms, they were 25-36% for 20-29 year-olds and 36-48% for 70-79 year-olds, while their leg FM remained the same with aging, i.e. 32-40%.

Conclusions: These data complete the published reference values for whole body composition, enabling physiological or pathological changes in limb composition to be identified in Caucasian populations living in the Mediterranean area.

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http://dx.doi.org/10.1016/j.clnu.2012.01.012DOI Listing

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