LU Yuan-lei (1894 - 1955) is the representative of Chinese and Western Medicine Convergence School in modern times. He is also the advocate of scientization of Traditional Chinese Medicine (TCM). TCM scientization is the refleetion of influence of Kampo medicine in modern China. Many academic viewpoints of LU Yuan-lei such as disease are caused by poison, scientifically elaborate ZHANG Zhong-jing's theories; thought on diseases not cured unless the medicine causes Mingxuan (a type of reaction in treatment'); the six meridians in Shanghanlun are not meridians in acupuncture; the value of pulse diagnosis and the sense of theory of 'Wu Yun Liu Qi' are influenced by Japanese Kampo medicine.
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Front Oncol
December 2024
Clinic for Gastroenterology and Gastrointestinal Oncology, University Medical Center Göttingen (UMG), Göttingen, Germany.
Pancreatic ductal adenocarcinoma (PDAC) is characterized by its poor prognosis. Traditional Japanese herbal medicine (Kampo), such as Juzentaihoto (a standardized combination of 10 herbal extracts), has shown immune modulatory effects, modulation of microcirculation, and amelioration of fatigue. It is administered to patients to prevent deterioration of cachexia and counteract side effects of chemotherapy.
View Article and Find Full Text PDFCureus
November 2024
Department of Integrative Physiology, Akita University Graduate School of Medicine, Akita, JPN.
The global incidence of mortality due to heart failure (HF) is on the rise, presenting a significant challenge in various regions, including Japan. There is an urgent need for innovative prevention and treatment strategies to address this issue. Traditional medicine, particularly Japanese Kampo medicine (JKM), has been proposed as a potential therapeutic approach and has undergone examination in clinical trials related to HF.
View Article and Find Full Text PDFFront Med (Lausanne)
December 2024
National Key Laboratory of Plant Molecular Genetics, CAS Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai, China.
Medicinal plants, also known as herbs, have been discovered and utilized in traditional medical practice since prehistoric times. Medicinal plants have been proven rich in thousands of natural products that hold great potential for the development of new drugs. Previously, we reviewed the types of Chinese traditional medicines that a Tang Dynasty monk Jianzhen (Japanese: Ganjin) brought to Japan from China in 742.
View Article and Find Full Text PDFNeuroscience
December 2024
Laboratory of Kampo Clinical Research, Oriental Medicine Research Center, School of Pharmacy, Kitasato University, Tokyo, Japan; Department of Pharmacognosy, School of Pharmacy, Kitasato University, Tokyo, Japan.
Infectious diseases are often concomitant with symptoms of lassitude and emotional disturbances, including depression, the so-called sickness behavior. Kososan, a Kampo (traditional Japanese herbal) formula, has been clinically used for depressive mood, with demonstrated efficacy in stress-induced depressive-like behavior mouse models. Additionally, our previous study has shown that nobiletin-rich kososan (NKS) prevents aging-related depressive-like behaviors and neuroinflammation in mice.
View Article and Find Full Text PDFDrugs Real World Outcomes
December 2024
Department of Pharmacy, Akita University Hospital, Akita, Japan.
Background: Kampo medicines are often used in Japan as therapy for the side effects induced by oral kinase inhibitors. However, the pharmacokinetic interactions between Kampo medicines and oral kinase inhibitors such as lenvatinib have not been studied.
Objective: We investigated the effects of Kampo medicines (rikkunshito, shakuyakukanzoto and goreisan) on the steady-state plasma trough concentration (C) of lenvatinib in patients with thyroid cancer.
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