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Extranodal Mantle Cell Lymphoma Presented as Bilateral Adrenal Masses on 18 F-FDG PET/CT and 68 Ga-DOTATATE PET/CT.
Clin Nucl Med
February 2025
Department of Nuclear Medicine, Marmara University Pendik Training and Research Hospital, Istanbul, Turkey.
Mantle cell lymphoma (MCL) is a rare type of B-cell non-Hodgkin lymphoma that commonly presents with constitutional symptoms, lymphadenopathy, and laboratory abnormalities. Although less common, extranodal involvement of MCL may be seen at initial presentation and most commonly occurs in the spleen, liver, bone marrow, and gastrointestinal tract. Adrenal involvement in MCL is extremely rare, and only a few cases have been reported in the literature.
View Article and Find Full Text PDFA case of mantle cell lymphoma with involvement of the entire gastrointestinal tract - Multiple endoscopic findings.
Rev Esp Enferm Dig
August 2024
Endoscopy, Northern Jiangsu People's Hospital, China.
Mantle cell lymphoma (MCL) is an aggressive B-cell lymphoma that occurs in some patients with gastric and intestinal involvement, but esophageal involvement is rare, and involvement of the entire gastrointestinal (GI) tract is even rarer. The endoscopic manifestations of MCL are mainly nodular or polypoid lesions. We report a rare case of MCL containing esophageal involvement of the entire GI tract with multiple endoscopic findings.
View Article and Find Full Text PDFHistopathological staging and differential diagnosis of marginal zone lymphoma of gastric mucosa-associated lymphoid tissue.
Eur J Gastroenterol Hepatol
June 2024
Shenzhen Polytechnic, Shenzhen, China.
The purpose of this study was to explore the histopathological staging and differential diagnosis of marginal zone lymphoma in gastric mucosa-associated lymphoid tissue (MALT lymphoma). We performed detailed histomorphology and immunohistochemistry investigations as well as genetic testing on endoscopic biopsy and endoscopic mucosal resection specimens from 18 patients with gastric MALT lymphoma. We found that gastric MALT lymphoma typically begins as a small, isolated area outside the lymphoid follicular mantle zone or proliferates in a multifocal, patchy manner, gradually spreads to the interfollicular zone, forming diffuse proliferation, invades the gastric mucosal glands, and infiltrates or proliferates into the center of peripheral reactive lymphoid follicles.
View Article and Find Full Text PDFFLI-1 is expressed in a wide variety of hematolymphoid neoplasms: a special concern in the differential diagnosis.
Clin Exp Med
January 2024
Department of Pathology, Seoul National University Boramae Hospital, 20 Boramae-Ro 5-Gil, Dongjak-Gu, Seoul, 07061, Republic of Korea.
Friend Leukemia Virus Integration 1 (FLI-1) is a member of E26 transformation-specific family of transcription factors that participates in hematopoietic and vascular endothelial cell development. Immunohistochemical detection of FLI-1 has been widely used to diagnose vascular tumors or, more evidently, Ewing's sarcoma. However, the expression pattern of FLI-1 in hematolymphoid neoplasms remains unclear.
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