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Progress in photoreceptor replacement therapy for retinal degenerative diseases.
Cell Insight
February 2025
Eye Center, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China.
Retinal degenerative diseases encompass a diverse range of eye conditions that result in blindness, many due to photoreceptor dysfunction and loss. Regrettably, current clinical treatments are frequently not overly effective. However, photoreceptor transplantation shows promise as a potential therapy for late-stage retinal degenerative diseases.
View Article and Find Full Text PDFIdentification of Gingival Inflammation Surface Image Features Using Intraoral Scanning and Deep Learning.
Int Dent J
January 2025
Department of Stomatology, Beijing Tongren Hospital, Capital Medical University, Beijing, China. Electronic address:
Introduction And Aim: The assessment of gingival inflammation surface features mainly depends on subjective judgment and lacks quantifiable and reproducible indicators. Therefore, it is a need to acquire objective identification information for accurate monitoring and diagnosis of gingival inflammation. This study aims to develop an automated method combining intraoral scanning (IOS) and deep learning algorithms to identify the surface features of gingival inflammation and evaluate its accuracy and correlation with clinical indicators.
View Article and Find Full Text PDFExperience of multidisciplinary cooperation in treating 15 extensively burned casualties：The Zhejiang LNG tanker explosion on 13 June 2020.
Burns
January 2025
Department of Burns and Wound Center, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hang Zhou 310009, PR China. Electronic address:
Background: On June 13, 2020, an explosion involving a liquefied natural gas (LNG) tanker truck occurred in eastern China. Fifteen patients with extremely severe burns (referred to as "June 13" patients) were treated in the burn-intensive care unit (ICU) joint ward within the general ICU.
Methods: A multidisciplinary treatment team comprising 129 doctors, 126 nurses, and 165 auxiliary staff members was assembled.
Comparative efficacy of robot-assisted therapy associated with other different interventions on upper limb rehabilitation after stroke: A protocol for a network meta-analysis.
PLoS One
January 2025
Innovation Center of Nursing Research, Nursing Key Laboratory of Sichuan Province, West China Hospital, Sichuan University/West China School of Nursing, Sichuan University, Chengdu, China.
Introduction: Post-stroke movement disorders are common, especially upper limb dysfunction, which seriously affects the physical and mental health of stroke patients. With the continuous development of intelligent technology, robot-assisted therapy has become a research hotspot in the upper limb rehabilitation of stroke patients in recent years. Many scholars have also integrated robot-assisted therapy with other interventions to improve rehabilitation outcomes.
View Article and Find Full Text PDFSymptom Network and Subgroup Analysis in Patients with Exacerbation of Chronic Obstructive Pulmonary Disease: A Cross-Sectional Study.
Int J Chron Obstruct Pulmon Dis
January 2025
Key Laboratory of Interventional Pulmonology of Zhejiang Province, Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, People's Republic of China.
Purpose: This study aims to construct a contemporaneous symptom network of inpatients with Exacerbation of Chronic Obstructive Pulmonary Disease (ECOPD) based on the symptom cluster, identify core and bridge symptoms, and patient subgroups with different symptom clusters based on individual differences in the intensity of patient symptom experiences.
Patients And Methods: This study used convenience sampling to collect demographic, symptom, auxiliary examination, and prognosis information of 208 inpatients with ECOPD from April 2022 to October 2023. The data underwent exploratory factor analysis (EFA), symptom network analysis, latent class analysis (LCA), Spearman correlation analysis, Wilcoxon signed-rank test, single-factor regression and multiple-factor stepwise regression.
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