Purpose: To analyze the complications of laparoscopy in different vascular structures using magnetic resonance imaging (MRI). MRI has become a key tool in laparoscopic surgery. During these procedures, pneumoperitoneum creation and placing the patient in the surgical position provoke different changes in the splachnic circulation.
Materials And Methods: Ten pigs were included in the study. MRI studies of the abdominal area were carried out in four different situations of abdominal pressure and body position.
Results: Changes in the area of the lumen of the portal vein and the abdominal aorta were analyzed in all situations. A significant reduction in the area of the abdominal aorta was observed after the pneumoperitoneum in supine and anti-Trendelemburg position. The lumen of the portal vein was significantly reduced in all analyzed situations except when placing the patient in anti-Trendelemburg without pneumoperitoneum, in which case the area was increased.
Conclusion: The creation of pneumoperitoneum provokes morphological changes in the lumen of different abdominal vessels as a consequence of the increase of pressure. Furthermore, the combination of pneumoperitoneum together with the anti-Trendelemburg position results in a more significant reduction of the lumen of the portal vein and the abdominal aorta.
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http://dx.doi.org/10.1002/jmri.23615 | DOI Listing |
Gastroenterology
December 2024
Division of Gastroenterology and Hepatology, Department of Medicine, Endeavor Health, Chicago, Illinois.
Description: Portal vein thromboses (PVTs) are common in patients with cirrhosis and are associated with advanced portal hypertension and mortality. The treatment of PVTs remains a clinical challenge due to limited evidence and competing risks of PVT-associated complications vs bleeding risk of anticoagulation. Significant heterogeneity in PVT phenotype based on anatomic, host, and disease characteristics, and an emerging spectrum of therapeutic options further complicate PVT management.
View Article and Find Full Text PDFSci Rep
November 2024
Department of Translational Medicine and Physiology, Elson S. Floyd College of Medicine, Washington State University, 412 E Spokane Falls Blvd, Spokane, WA, 99210, USA.
Recent research suggests that microbial molecules translocated from the intestinal lumen into the host's internal environment may play a role in various physiological functions, including sleep. Previously, we identified that butyrate, a short-chain fatty acid produced by intestinal bacteria, and lipoteichoic acid, a cell wall component of gram-positive bacteria, induce sleep when their naturally occurring translocation is mimicked by direct delivery into the portal vein. Building upon these findings, we aimed to explore the sleep signaling potential of intraportally administered lipopolysaccharide (LPS), a primary component of gram-negative bacterial cell walls, in rats.
View Article and Find Full Text PDFBr J Nutr
November 2024
Graduate School of Agriculture, Hokkaido University, Kita-9, Nishi-9, Kita-ku, Sapporo060-8589, Japan.
Postprandially, amino acids and di/tripeptides are thought to be primarily absorbed in the proximal small intestine. However, there have been no demonstrations of regional differences in amino acid transport dynamics between the proximal and distal small intestines. We monitored plasma amino acid responses in the jejunal and ileal mesenteric veins of rats after oral administration of a diet or an amino acid mixture (Expt 1) and in the portal vein after direct administration of the amino acid mixture into the lumen of the jejunum or ileum (Expt 2).
View Article and Find Full Text PDFNano Lett
November 2024
Groningen Biomolecular Sciences & Biotechnology Institute, University of Groningen, 9747 AG Groningen, The Netherlands.
After the successful sequencing of nucleic acids, nanopore technology has now been applied to proteins. Recently, it has been demonstrated that an electro-osmotic flow can be used to induce the transport of unraveled polypeptides across nanopores. Polypeptide translocation, however, is too fast for accurate reading its amino acid compositions.
View Article and Find Full Text PDFJ Toxicol Environ Health B Crit Rev
November 2024
Center for Medical Research, Medical University of Graz, Graz, Austria.
Microplastic particles (MPs) have been detected in a variety of environmental samples, including soil, water, food, and air. Cellular studies and animal exposures reported that exposure to MPs composed of different polymers might result in adverse effects at the portal of entry (local) or throughout the body (systemic). The most relevant routes of particle uptake into the body are oral and respiratory exposure.
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