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Effect of blindfolding the lead resuscitator on frequency of closed-loop communication during veterinary cardio-pulmonary resuscitation training: a randomized, controlled pilot study.
Front Vet Sci
January 2025
Dick White Referrals, part of Linnaeus Veterinary Limited, Cambridgeshire, United Kingdom.
Objective: To evaluate the effect of blindfolding the lead resuscitator during veterinary cardiopulmonary resuscitation (CPR) simulation training sessions on frequency of completed closed-loop communication statements (CLC).
Design: Ten groups of staff volunteers were recruited for a prospective, randomized, blinded, observational pilot study over a 6-month period. Additionally, two associated online questionnaires were completed by participants.
Col1A1 as a new decoder of clinical features and immune microenvironment in ovarian cancer.
Front Immunol
January 2025
Department of Gynecology, Sichuan Provincial Women's and Children's Hospital, The Affiliated Women's and Children's Hospital of Chengdu Medical College, Chengdu, Sichuan, China.
Backgrounds: Collagen type I alpha 1 chain (COL1A1) is a key protein encoding fibrillar collagen, playing a crucial role in the tumor microenvironment (TME) due to its complex functions and close association with tumor invasiveness. This has made COL1A1 a focal point in cancer biology research. However, studies investigating the relationship between COL1A1 expression levels and clinical characteristics of ovarian cancer (OC) remain limited.
View Article and Find Full Text PDFDrp1-associated genes implicated in sepsis survival.
Front Immunol
January 2025
Center for Translational Science, Florida International University, Port Saint Lucie, FL, United States.
Sepsis is a severe and life-threatening medical syndrome that can lead to organ failure and death. Despite advances in medical treatment, current therapies are often inadequate, with high septic mortality rates. Therefore, there is a critical need for reliable prognostic markers to be used in clinical settings to improve the management and outcomes of patients with sepsis.
View Article and Find Full Text PDFDeciphering hub genes and immune landscapes related to neutrophil extracellular traps in rheumatoid arthritis: insights from integrated bioinformatics analyses and experiments.
Front Immunol
January 2025
Department of Rheumatology, The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, Anhui, China.
Background: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by synovial inflammation and progressive joint destruction. Neutrophil extracellular traps (NETs), a microreticular structure formed after neutrophil death, have recently been implicated in RA pathogenesis and pathological mechanisms. However, the underlying molecular mechanisms and key genes involved in NET formation in RA remain largely unknown.
View Article and Find Full Text PDFPotential role of gut-related factors in the pathology of cartilage in osteoarthritis.
Front Nutr
January 2025
Department of Pediatric Orthopaedics, Shengjing Hospital of China Medical University, Shenyang, China.
Osteoarthritis (OA) is a common progressive degenerative disease. Gut microbiota (GM) and their metabolites have been closely associated with the onset, progression, and pathology of OA. GM and their metabolites may influence the cartilage directly, or indirectly by affecting the gut, the immune system, and the endocrine system.
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