Objective: The objective of this study was to report a case of new onset refractory pain from intrapleural migration of a spinal catheter five months after the implantation of an intrathecal drug delivery system (IDDS).
Materials And Methods: A 57-year-old man had intractable pain because of multiple intradural spinal explorations for tethered cord release. His pain was effectively treated with intrathecal morphine via an IDDS. Five months after the implantation, the patient developed return of the original pain more than two weeks after intrapleural migration of the intrathecal catheter.
Results: The migration was documented by computed tomography, and repositioning of the catheter rendered the patient comfortable. The gradual onset of pain may have been due to decreasing delivery of drug to the cerebrospinal fluid as the catheter tip migrated further away from the dura. To our knowledge, this complication has not been reported in the literature.
Conclusion: Physicians and nursing staff that place and manage an IDDS should be aware of this complication.
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http://dx.doi.org/10.1111/j.1525-1403.2011.00423.x | DOI Listing |
J Thorac Dis
November 2024
Department of Thoracic Surgery, Robert Schuman Hospitals Luxembourg, Luxembourg, Luxembourg.
Background: Kirschner wires or pins were widely used for osteosynthesis in trauma surgery. Breakage of osteosynthesis material and intra-thoracic migration is a complication that has occasionally been described. We reviewed the literature to study the frequency and pathophysiology of such migrations.
View Article and Find Full Text PDFAsian J Neurosurg
September 2024
Department of Neurosurgery, Kasturba Medical College and Hospital, Udupi, Karnataka, India.
Stem Cells Transl Med
August 2024
School of Medicine, Keele University, Staffordshire, United Kingdom.
Oncolytic adenoviruses have emerged as a promising therapeutic approach for cancer therapy. However, systemic delivery of the viruses to metastatic tumors remains a major challenge. Mesenchymal stem cells (MSCs) possess tumor tropism property and can be used as cellular vehicles for delivering oncolytic adenoviruses to tumor sites.
View Article and Find Full Text PDFSurg Laparosc Endosc Percutan Tech
April 2024
Centre for Surgery Zurich, Thoracic and Visceral Surgery, Hirslanden Private Hospital Group, Zurich, Switzerland.
Background: Foreign bodies within the pleura and pancreas are infrequent, and the approaches to their treatment still a subject of debate. There is limited knowledge particularly regarding glass foreign bodies.
Methods: We present a case involving large glass splinters in the pleura and pancreas, with an unknown entry point.
Nutrients
March 2023
Program in Nutrition and Food Science, Fu Jen Catholic University, New Taipei City 242, Taiwan.
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