Synthesis of benzisoxazolines by the coupling of arynes with nitrones.

J Org Chem

Department of Chemistry, Iowa State University, Ames, Iowa 50011, USA.

Published: March 2012

A variety of substituted benzisoxazolines have been synthesized by the [3 + 2] cycloaddition of nitrones and arynes. The reaction scope is broad, the reaction conditions are mild, and the process tolerates a variety of functional groups.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293248PMC
http://dx.doi.org/10.1021/jo2025064DOI Listing

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