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Background: Insulin resistance (IR) is a common pathophysiologic feature in patients with polycystic ovary syndrome (PCOS). However, there have been no studies investigating the association of IR surrogates with pregnancy outcomes in women with PCOS undergoing in vitro fertilization (IVF). Therefore, we explored the association between these factors among PCOS patients.

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Article Synopsis
  • Preterm birth significantly impacts parents' mental health, and posttraumatic growth (PTG) can help them cope with this trauma, though research on PTG in this context is limited.
  • A study involving 160 parents in Shenzhen, China, found that most had low to medium PTG levels, with influences like older gestational age, higher Apgar scores, positive coping styles, and better social support correlating with higher PTG.
  • The findings highlight the importance of social support and effective coping mechanisms in fostering PTG among parents dealing with the challenges of having a preterm infant.
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Background: Despite global declines in child mortality rates, Africa's reduction is lagging behind other regions. Neonatal survival remains a key priority in the sustainable development agenda. Promoting neonatal care practices at the individual and community levels is essential, and technology-based interventions can effectively reach potential future mothers.

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CLP-Net: an advanced artificial intelligence technique for localizing standard planes of cleft lip and palate by three-dimensional ultrasound in the first trimester.

BMC Pregnancy Childbirth

January 2025

National-Regional Key Technology Engineering Laboratory for Medical Ultrasound, School of Biomedical Engineering, Health Science Center, Shenzhen University, Xueyuan Blvd, Nanshan, Shenzhen, Guangdong, China.

Background: Early diagnosis of cleft lip and palate (CLP) requires a multiplane examination, demanding high technical proficiency from radiologists. Therefore, this study aims to develop and validate the first artificial intelligence (AI)-based model (CLP-Net) for fully automated multi-plane localization in three-dimensional(3D) ultrasound during the first trimester.

Methods: This retrospective study included 418 (394 normal, 24 CLP) 3D ultrasound from 288 pregnant woman between July 2022 to October 2024 from Shenzhen Guangming District People's Hospital during the 11-13 weeks of pregnancy.

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Gestational - age - specific reference intervals for blood pressure in normal pregnancy in a Southern Chinese population.

BMC Pregnancy Childbirth

January 2025

Department of Obstetrics, Longgang Maternity and Child Institute of Shantou University Medical College, Longgang District Maternity & Child Healthcare Hospital, Shenzhen, Guangdong, 518172, China.

Objective: Physiological blood pressure changes in pregnancy are insufficiently defined. This paper describes the blood pressure changes across healthy pregnancies in a Southern Chinese population to present gestational - age - specific blood pressure ranges with smoothed centiles (3rd, 10th, 50th, 90th, and 97th).

Methods: Antenatal blood pressure measurements [median (interquartile range) 9 (8 - 10) per woman] were repeated in 17, 776 women from a Southern China population.

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