AI Article Synopsis
- A meta-analysis was conducted to compare the number of lymph nodes harvested during laparoscopic versus open colorectal cancer surgery, examining 24 randomized controlled trials with a total of 6,264 participants.
- Both surgical methods showed no significant difference in lymph node harvest (weighted mean difference of -0.25; P=0.542), indicating that laparoscopic surgery is as effective as open surgery in this regard.
- The findings emphasize that surgeons should focus on lymph node excision, as it is important for the long-term benefits of patients.
Article Abstract
Increasing researches have reported the safety and efficacy of laparoscopic versus open approach for colorectal cancer resection; however, the number of lymph nodes harvested in the 2 approaches is still unclear. This meta-analysis is to compare the number of lymph node harvested in these 2 methods. We searched the PUBMED, the EMBASE, and the Cochrane Library up to July 1, 2011 for relevant studies. Twenty-four randomized controlled trials, comprising 6264 participants, met our criterion. We found no difference in the number of lymph nodes harvested in these 2 approaches (weighted mean difference=-0.25; 95% confidence interval, -0.57 to 0.08; P=0.542), as well as in subgroups of colon cancer and of rectal cancer. Our meta-analysis suggests that laparoscopic surgery could achieve the same effectiveness with open surgery in relation to lymph node harvested. Surgeons should pay appropriate attention on the excision of lymph nodes, which are associated with long-term benefits of patients.
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| http://dx.doi.org/10.1097/SLE.0b013e3182432b49 | DOI Listing |
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