Purpose: The aim of this study was to evaluate the outcome of arthroscopic partial repair and margin convergence of irreparable large to massive rotator cuff tears.
Methods: Between January 2003 and July 2008, 27 patients who met the inclusion criteria underwent arthroscopic partial repair and margin convergence of irreparable large to massive rotator cuff tears. An irreparable tear was defined as a tear with a minimum anterior-to-posterior width of 3 cm or larger, where it was not feasible to completely cover the humeral head with the cuff at the time of surgery.
Results: The mean preoperative tear size was 42.1 ± 6.2 mm. The mean size of the postoperative residual defect in the repaired tendon along the medial margin of the greater tuberosity was 12.0 ± 5.5 mm. All shoulder scores showed improvement. The Simple Shoulder Test improved from 5.1 ± 1.2 to 8.8 ± 2.1 (P < .001), the Constant score from 43.6 ± 7.9 to 74.1 ± 10.6 (P < .001), and the University of California, Los Angeles score from 10.5 ± 3.0 to 25.9 ± 5.0 (P < .001). Both Constant and University of California, Los Angeles shoulder scores also showed an inverse correlation with defect size. We compared muscle strength between the affected and contralateral sides and found that the strength of the affected side was not restored to the same level as the contralateral side (P < .001).
Conclusions: Arthroscopic partial repair and margin convergence showed satisfactory short-term outcomes in irreparable large to massive rotator cuff tears. Thus it is suggested that, even in a large to massive tear that appears irreparable, attempting to repair it as much as possible to possibly convert it into a functional rotator cuff tear by re-creating a balanced forced couple can be helpful in reducing pain, as well as improving functional outcomes.
Level Of Evidence: Level IV, therapeutic case series.
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http://dx.doi.org/10.1016/j.arthro.2011.11.018 | DOI Listing |
Arthrosc Tech
December 2024
Department of Orthopaedic Surgery, University of Missouri, Columbia, Missouri, USA.
Rotator cuff tears are a common cause of shoulder pain and dysfunction. Recent and historical reports suggest that a sizable percentage of patients may experience a retear of the rotator cuff despite surgical intervention. Multiple biological and mechanical factors can influence outcomes after rotator cuff surgery, including patient age, rotator cuff tear size, chronicity, and rotator cuff tissue quality.
View Article and Find Full Text PDFNat Med
January 2025
Department of Neurosurgery, NYU Langone Health, New York, NY, USA.
The adoption of large language models (LLMs) in healthcare demands a careful analysis of their potential to spread false medical knowledge. Because LLMs ingest massive volumes of data from the open Internet during training, they are potentially exposed to unverified medical knowledge that may include deliberately planted misinformation. Here, we perform a threat assessment that simulates a data-poisoning attack against The Pile, a popular dataset used for LLM development.
View Article and Find Full Text PDFGut Liver
January 2025
Department of Pathology, Seoul National University College of Medicine, Seoul, Korea.
Background/aims: Fibronectin (FN) has recently been identified as being overexpressed in patients with hepatocellular carcinoma (HCC) and deemed a promising biomarker of vascular invasion. The aim of this study was to examine the patterns of FN expression in HCC cells and their clinicopathological significance, such as their association with vascular invasion and angiogenesis patterns.
Methods: Immunohistochemical analysis of FN was conducted using tissue microarrays from 258 surgically resected HCCs and matched nontumorous liver tissues.
Arthroscopy
January 2025
Department of Orthopaedic Surgery, New England Baptist Hospital, Boston, MA USA. Electronic address:
In terms of rotator cuff repair, there is a goal for complete repair and healing, as rotator cuff integrity correlates with clinical and functional results. Retear has been shown to have a significant influence on progression toward osteoarthritis, and patients with an intact supraspinatus show superior abduction and flexion strength. However, in cases where complete repair may not be possible and/or cost limitations may prohibit augmentation, partial repair can provide a respectable outcome.
View Article and Find Full Text PDFCurr Opin Struct Biol
January 2025
Sorbonne Université, CNRS, IBPS, Laboratory of Computational and Quantitative Biology (LCQB), UMR 7238, 75005 Paris, France.
The mRNA splicing machinery has been estimated to generate 100,000 known protein-coding transcripts for 20,000 human genes (Ensembl, Sept. 2024). However, this set is expanding with the massive and rapidly growing data coming from high-throughput technologies, particularly single-cell and long-read sequencing.
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