Objective: To explore the prognostic effects of anemia among the mechanically ventilated patients.
Methods: A prospective observational study was undertaken in a 12-bed intensive care unit (ICU). Patients requiring mechanical ventilation for at least 72 hours and hemoglobin (Hb)≥100 g/L were enrolled. Serum erythropoietin (EPO), Fe(3+), transferrin (TRF) levels were measured as baseline when they were enrolled and were repeated at day 3, 7 and 14. According to Hb concentration at day 3, patients were divided into anemia group (defined as Hb<100 g/L) and non-anemia group. Serum EPO, Fe(3+), TRF at day 1, 3 and 7, and mean amount of blood transfusion within 14 days, mean volume of blood drawn daily in 3, 7 and 14 days, the survival rate with unassisted breathing at day 28, ICU mortality, length of ICU stay, ventilator days, length of hospital stay and 28-day mortality were compared.
Results: Forty mechanically ventilated patients were enrolled and divided into anemia group (n = 18) and non-anemia group (n = 22). It was shown that the anemia group had lower serum Fe(3+) concentration, and higher serum EPO and TRF. The anemia group also had more transfusion [U: 4.0 (2.0, 6.0) vs. 2.0 (0.0, 2.0), P < 0.01], longer length of hospital stay [days: 35.0 (16.5, 51.6) vs. 24.5 (10.0, 35.8), P < 0.05], decreased rate of survival with unassisted breathing at day 28 (44.4% vs. 72.7%, P < 0.05) and higher ICU mortality (44.4% vs. 13.6%, P < 0.05). But there were no significant differences between anemia group and control group in mechanical ventilated days (days: 18.3 ± 10.8 vs. 11.6 ± 8.2, P > 0.05), length of ICU stay [days: 16.5 (8.0, 21.5) vs. 11.0 (5.8, 18.3),P > 0.05] and hospital mortality (61.1% vs. 31.8%, P > 0.05).
Conclusion: The anemic patients had longer ventilator days, hospital stay, higher ICU mortality, and lower rate of survival with unassisted breathing at day 28.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Peripheral oxygen saturation levels as a guide to avoid hyperoxia: an observational study.
Scand J Trauma Resusc Emerg Med
January 2025
Department of Acute Care, University Medical Centre Groningen, Groningen, the Netherlands.
Background: As iatrogenic hyperoxia has been related to adverse outcomes in critically ill patients, guidelines advise to titrate oxygen to physiological levels. In the prehospital setting where partial arterial oxygen (PaO) values are often not readily available, titration of oxygen is based on peripheral oxygen saturations (SpO2). In this study we aimed to investigate the efficacy of SpO guided oxygen titration in the prevention of hyperoxia.
View Article and Find Full Text PDFMultimodal ultrasound assessment of the injection therapy in lateral epicondylitis: a retrospective observational study.
BMC Musculoskelet Disord
January 2025
Orthopedics Department of Zhejiang Rongjun Hospital, Jiaxing City, Zhejiang Province, China.
Background: At present, there is a dearth of objective methodologies for assessing the effectiveness of treatments for Lateral Epicondylitis (LE). This study examined 73 patients suffering from tennis elbow using a multimodal ultrasound approach and investigated the correlation between pertinent indicators and clinical scores.
Methods: 73 patients diagnosed with unilateral tennis elbow by interventional ultrasound at Zhejiang Rongjun Hospital were included in the study.
Delirium at the intensive care unit and long-term survival: a retrospective study.
BMC Neurol
January 2025
Institute for Intensive Care Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Background: Delirium is a common complication in patients at the intensive care unit (ICU) and is associated with prolonged ICU-stay and hospitalization and with increased morbidity. The impact of ICU-delirium on long-term survival is not clearly understood.
Methods: This retrospective single center observational study was conducted at the Institute of Intensive Care Medicine at the University Hospital Zurich, Switzerland.
Association between edaravone use and activities of daily living in older patients with atherothrombotic stroke: an observational study using Japanese real-world data.
BMC Geriatr
January 2025
Department of Pharmacy, Faculty of Pharmacy, Musashino University, 1-1-20 Shinmachi Nishitokyo-Shi, Tokyo, 202-8585, Japan.
Background: Edaravone is marketed in nine countries, although only Japan has approved edaravone for improvement of neurological symptom, disability of activities of daily living (ADL), and functional disability associated with acute stroke. This study aimed to elucidate the association of edaravone use with ADL using real-world data of older patients with atherothrombotic stroke.
Methods: This retrospective observational research using the Medical Data Vision database in Japan included patients aged 65 years and older who had acute ischemic stroke of the atherothrombotic subtype.
The Role of Ultrasonographic Assessment of Optic Nerve Sheath Diameter in Prediction of Sepsis-Associated Encephalopathy: Prospective Observational Study.
Neurocrit Care
January 2025
Department of Anesthesia, Intensive Care, and Pain Management, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Background: Ultrasonographic optic nerve sheath diameter (ONSD) is a satisfactory noninvasive intracranial pressure (ICP) monitoring test. Our aim was to evaluate ONSD as an objective screening tool to predict and diagnose ICP changes early in sepsis-associated encephalopathy (SAE).
Methods: Our prospective observational study was conducted on patients with sepsis, and after intensive care unit (ICU) admission, the time to diagnose SAE was recorded, and patients were divided into a non-SAE group including conscious patients with sepsis and a SAE group including patients with sepsis with acute onset of disturbed conscious level.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!