Purpose: To evaluate the long-term effects on corneal endothelium after pediatric cataract surgery.
Methods: We conducted a cross-sectional study of 58 eyes operated for unilateral pediatric cataract with a mean age at the time of cataract surgery of 38.2 ± 41.6 months (range, 1-171 months) and a mean follow-up between cataract surgery and assessments of 149.6 ± 69.8 months (range, 30-319 months). Parameters that were studied were endothelial cell density, hexagonal cell percentage, and coefficient of variation of cell area. Parameters in the operated eyes were compared with the normal unoperated eyes.
Results: Regarding the endothelial cell density (Student t test, P = 0.000), there are statistically significant differences between groups (operated and unoperated eyes), with an average loss of 9.2% in the operated eyes. With the hexagonal cell percentage (Student t test, P = 0.508) and the coefficient of variation of cell area (Wilcoxon test, P = 0.595), there was an absence of statistically significant differences between the operated and unoperated eyes.
Conclusions: Endothelial cell loss was 9.2%, and no difference was found in hexagonal cell percentage and coefficient of variation of cell area between the operated and unoperated eyes 12.5 years after unilateral pediatric cataract surgery.
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http://dx.doi.org/10.1097/ICO.0b013e31820cd74a | DOI Listing |
Redox Biol
January 2025
Department of Ophthalmology, Kornel Gibiński University Clinical Center, Medical University of Silesia, Katowice, Poland; Department of Ophthalmology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Katowice, Poland; GlaucoTech Co, Katowice, Poland.
Myopia is an evolving global health challenge, with estimates suggesting that by 2050 it will affect half of the world's population, becoming the leading cause of irreversible vision loss. Moreover, myopia can lead to various complications, including the earlier onset of cataracts. Given the progressive aging of the population and the increase in life expectancy, this will contribute to a rising demand for cataract surgery, posing an additional challenge for healthcare systems.
View Article and Find Full Text PDFOphthalmol Ther
January 2025
Pediatric Ophthalmology and Strabismus Division, King Khaled Eye Specialist Hospital, Al Urubah Branche Rd., West Building 2nd Floor, 11462, Riyadh, Saudi Arabia.
Introduction: Persistent fetal vasculature (PFV) is a congenital anomaly associated with significant surgical challenges, including a high risk of postoperative retinal detachment (RD). This study aimed to evaluate the impact of surgical approach and axial length (AL) on RD risk and visual outcomes in pediatric PFV management.
Methods: A retrospective cohort study was conducted involving 76 eyes of 74 patients who underwent cataract surgery for PFV between 2014 and 2022.
Clin Ophthalmol
January 2025
Department of Pediatrics, Faculty of Medicine, Chulalongkorn University Bangkok, Bangkok, Thailand.
Purpose: To describe the demographic profile, clinical characteristics, and treatment trends of Fuchs endothelial corneal dystrophy (FECD) in Thai patients, reflecting the evolving landscape of corneal transplantation in this region.
Patients And Methods: This retrospective cohort study included 900 patients (1,743 eyes) diagnosed with FECD at a tertiary referral center in Thailand between January 2017 and June 2023. Demographic, clinical, and surgical data were analyzed, focusing on best-corrected visual acuity (BCVA), central corneal thickness (CCT), endothelial cell density (ECD), surgical interventions, and graft survival rate.
Sensors (Basel)
December 2024
Ophthalmic Instrumentation Development Lab, The Wilmer Eye Institute, The Johns Hopkins University School of Medicine, Wilmer 233, 600 N. Wolfe St., Baltimore, MD 21287, USA.
Signal amplitudes obtained from retinal scanning depend on numerous factors. Working with polarized light to interrogate the retina, large parts of which are birefringent, is even more prone to artifacts. This article demonstrates the necessity of using normalization when working with retinal birefringence scanning signals in polarization-sensitive ophthalmic instruments.
View Article and Find Full Text PDFVaccines (Basel)
December 2024
Global Immunization Division, United States Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.
Background/objectives: Congenital rubella syndrome (CRS) is a constellation of serious multi-organ birth defects following rubella virus infection during early pregnancy. Countries in which rubella vaccination has not yet been introduced can have a high burden of this disease. Data on CRS burden and epidemiology are needed to guide the introduction of a rubella vaccine and monitor progress for rubella elimination, but the multi-system nature of CRS manifestations and required specialized testing creates a challenge for conducting CRS surveillance in developing settings such as Sudan.
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