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Neurobehavioral Symptoms Partially Mediate the Effects of Depression and PTSD on Participation for Veterans With Mild Traumatic Brain Injury: A Cross-Sectional Study.
J Head Trauma Rehabil
January 2025
Author Affiliations: Department of Physical Medicine and Rehabilitation (Drs Wyrwa, Burke, Forster, and Kinney), Departments of Physical Medicine and Rehabilitation, Psychiatry, and Neurology (Dr Brenner), University of Colorado, Anschutz Medical Campus, Aurora, Colorado; and VA Rocky Mountain Mental Illness Research, Education, and Clinical Center (MIRECC) (Dr Brenner, Mr Yan, Ms Schneider, Mr King, and Drs Forster and Kinney), Aurora, Colorado.
Objective: To examine whether neurobehavioral symptoms mediate the relationship between comorbid mental health conditions (major depressive disorder [MDD] and/or posttraumatic stress disorder [PTSD]) and participation restriction among Veterans with mild traumatic brain injury (mTBI).
Setting: Veterans Health Administration (VHA).
Participants: National sample of Veterans with mTBI who received VHA outpatient care between 2012 and 2020.
Assessing Traumatic Brain Injury in Refugees: Feasibility, Usability, and Prevalence Insights From a US-Based Clinical Sample.
J Head Trauma Rehabil
January 2025
Author Affiliations: Boston University School of Public Health, Boston, Massachusetts (Ms Sherman Rosa); Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts (Mr Nadal); and Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts (Dr Saadi).
Objective: This study assessed (1) the feasibility and usability of traumatic brain injury (TBI) assessment using the Ohio State University TBI Identification Method (OSU-TBI-ID) in a sample of English and Spanish-speaking refugees and asylum seekers (hereafter refugees), and (2) the prevalence and characteristics of TBI in this population.
Setting And Participants: Refugees seeking care from Massachusetts General Hospital (MGH) Asylum Clinic, the MGH Chelsea HealthCare Center, and other asylum programs in the Greater Boston Area.
Design And Main Measures: Bilingual clinical research coordinators screened 158 English and Spanish-speaking refugees using the OSU-TBI-ID.
Sex Differences in Early/Unplanned Separation Among US Service Members With a History of Mild Traumatic Brain Injury.
J Head Trauma Rehabil
January 2025
Author Affiliations: Program Executive Office, Defense Healthcare Management Systems, Arlington, Virginia (Ms Wal and Dr Caban); National Center for Collaborative Healthcare Innovation (NCCHI), VA Palo Alto Health Care System, Palo Alto, California (Mr Hoover); Department of Health Law, Policy and Management, Boston University School of Public Health, Boston, Massachusetts (Dr Adams); Veterans Health Administration Rocky Mountain Mental Illness Research Education and Clinical Center, Aurora, Colorado (Drs Adams and Forster); Department of Physical Medicine & Rehabilitation, University of Colorado, Anschutz Medical Campus, Aurora, Colorado (Dr Forster); and Uniformed Services University of the Health Sciences, Graduate School of Nursing, Bethesda, Maryland (Dr Engler).
Objective: To investigate the incidence of early/unplanned (E/U) separations following mild traumatic brain injury (mTBI) and assess whether sex impacts the hazard of separation.
Setting: Military Health System (MHS).
Participants: Active duty service members (N = 75,730) with an initial mTBI diagnosis in military records between January 2011 and January 2018.
Diagnosis of traumatic liver injury on computed tomography using machine learning algorithms and radiomics features: The role of artificial intelligence for rapid diagnosis in emergency rooms.
J Res Med Sci
December 2024
Department of Biostatistics, Student Research Committee, University of Medical Sciences, Kermanshah, Iran.
Background: The initial assessment of trauma is a time-consuming and challenging task. The purpose of this research is to examine the diagnostic effectiveness and usefulness of machine learning models paired with radiomics features to identify blunt traumatic liver injury in abdominal computed tomography (CT) images.
Materials And Methods: In this study, 600 CT scan images of people with mild and severe liver damage due to trauma and healthy people were collected from the Kaggle dataset.
The transcriptional response of cortical neurons to concussion reveals divergent fates after injury.
Nat Commun
January 2025
Unit on the Development of Neurodegeneration, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.
Traumatic brain injury (TBI) is a risk factor for neurodegeneration, however little is known about how this kind of injury alters neuron subtypes. In this study, we follow neuronal populations over time after a single mild TBI (mTBI) to assess long ranging consequences of injury at the level of single, transcriptionally defined neuronal classes. We find that the stress-responsive Activating Transcription Factor 3 (ATF3) defines a population of cortical neurons after mTBI.
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