Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide. New diagnostic and therapeutic strategies are needed to mitigate this public health issue. Advances in nanotechnology have generated innovative strategies for diagnosis and therapy in a variety of diseases, foremost in cancer. Based on these studies, a novel concept referred to as nanomedical theranostics, or the combinatory application of nanoparticulate agents to allow diagnostic therapy, is being explored to enable image-guided, personalized, or targeted treatment. Preclinically, theranostics have been gradually applied to CVD with several interesting and encouraging findings. This article summarizes studies and challenges of nanotheranostic strategies in CVD. It also evaluates nanotheranostic strategies that may potentially be utilized to benefit patients.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261407PMC
http://dx.doi.org/10.1007/s12410-011-9120-6DOI Listing

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Article Synopsis
  • * Nanocarriers are emerging as promising tools for improving drug targeting, reducing side effects, and enhancing diagnostic capabilities in cardiovascular medicine.
  • * The field of cardiovascular nanomedicine is still developing, but ongoing innovations in nanocarrier technology may significantly advance treatment effectiveness and disease management.
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