Embryonic stem cell strategies to explore neural crest development in human embryos.

Dev Biol

Institut Curie, INSERM U1021, CNRS, UMR 3347, F-91405 Orsay, France.

Published: June 2012

AI Article Synopsis

  • Researchers have faced significant challenges in directing embryonic stem cell development in lab settings over the last ten years.
  • Various protocols have been formulated to create neural crest derivatives under different conditions.
  • This text outlines the strategies for achieving neural crest specification and highlights the markers for identifying human neural crest cells.

Article Abstract

Controling embryonic stem cell fate in vitro has been a major challenge in the past decade. Several protocols have been developed to obtain neural crest derivatives in culture, using more or less defined conditions. Here, we present various strategies used to date to obtain neural crest specification and the markers that can be used to identify human neural crest cells.

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Source
http://dx.doi.org/10.1016/j.ydbio.2012.01.016DOI Listing

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