AI Article Synopsis
- The study explores the prevalence of late gadolinium enhancement (LGE) in patients diagnosed with tachycardia-induced cardiomyopathy (TICMP) caused by idiopathic ventricular arrhythmias.
- Among 298 patients with frequent PVCs and/or VT, 27 (9.1%) were found to have reduced left ventricular ejection fraction (LVEF), with 22 showing improvement after treatment, indicating TICMP.
- LGE was identified in only 5% of TICMP patients while 80% of those with primary cardiomyopathy had LGE, suggesting that LGE is a rare finding in TICMP, and further research is needed to understand its implications on recovery.
Article Abstract
Background: Idiopathic ventricular arrhythmias in the form of monomorphic premature ventricular contractions (PVC) and/or ventricular tachycardia (VT) can cause tachycardia-induced cardiomyopathy (TICMP). The aim of this study was to determine the prevalence of late gadolinium enhancement (LGE) in patients with TICMP caused by idiopathic ventricular arrhythmias.
Methods: The study population consisted of 298 consecutive patients (174 F/124 M; mean age 45±17 years) with frequent PVCs and/or VT. TICMP was defined as left ventricular ejection fraction (LVEF) of ≤50% in the absence of any detectable underlying heart disease and improvement of LVEF≥15% after effective treatment of index ventricular arrhythmia.
Results: Twenty-seven (9.1%) patients found to have LVEF≤50% and diagnosed as presumptive TICMP. Improvement in LVEF after effective treatment of index ventricular arrhythmia was observed in 22 of 27 patients (TICMP group; mean PVC burden of 30.8±9.9%). LVEF did not improve in five of 27 patients (primary cardiomyopathy group; mean PVC burden of 28.8±10.1%). LGE-cardiac magnetic resonance (CMR) imaging was performed in 19 of 22 patients with TICMP and one patient (5%) had LGE. All five patients with primary cardiomyopathy underwent LGE-CMR imaging and four patients (80%) had LGE.
Conclusions: LGE is a rare finding in patients with TICMP caused by idiopathic ventricular arrhythmias. LGE-CMR can be used in the diagnostic work-up of patients with TICMP. Further prospective studies are required to determine the role of LGE-CMR in predicting the recovery of left ventricular systolic dysfunction in patients with presumptive TICMP.
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| http://dx.doi.org/10.1111/j.1540-8159.2011.03324.x | DOI Listing |
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View Article and Find Full Text PDFLate gadolinium enhancement CMR in patients with tachycardia-induced cardiomyopathy caused by idiopathic ventricular arrhythmias.
Pacing Clin Electrophysiol
April 2012
Department of Cardiology, Ege University School of Medicine, Kent Hospital, Izmir, Turkey.
Article Synopsis
- The study explores the prevalence of late gadolinium enhancement (LGE) in patients diagnosed with tachycardia-induced cardiomyopathy (TICMP) caused by idiopathic ventricular arrhythmias.
- Among 298 patients with frequent PVCs and/or VT, 27 (9.1%) were found to have reduced left ventricular ejection fraction (LVEF), with 22 showing improvement after treatment, indicating TICMP.
- LGE was identified in only 5% of TICMP patients while 80% of those with primary cardiomyopathy had LGE, suggesting that LGE is a rare finding in TICMP, and further research is needed to understand its implications on recovery.
Tachycardia-induced cardiomyopathy in patients with idiopathic ventricular arrhythmias: the incidence, clinical and electrophysiologic characteristics, and the predictors.
J Cardiovasc Electrophysiol
June 2011
Department of Cardiology, Ege University School of Medicine, Izmir, Turkey.
Introduction: Idiopathic ventricular arrhythmias in the form of monomorphic premature ventricular contractions (PVC) and/or ventricular tachycardia (VT) can cause tachycardia-induced cardiomyopathy (TICMP). The aim of this study was to determine the incidence, clinical and electrophysiologic characteristics, and the predictors of TICMP in patients with idiopathic ventricular arrhythmias.
Methods: Study population consisted of 249 consecutive patients (148 F/101 M, 45 ± 20 y/o) with frequent PVCs and/or VT.
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