Selective atrial vagal denervation guided by evoked vagal reflex to treat refractory vasovagal syncope.

Pacing Clin Electrophysiol

Department of Cardiology, Changzheng Hospital, Second Military Medical University, Shanghai, China.

Published: July 2012

A 57-year-old woman with refractory vasovagal syncope and a sinus pause of 6.8 seconds during tilt-table test accepted the suggestion of atrial vagal denervation. Radiofrequency pulses were delivered on positive vagal reflex sites according to the standard of heart rate (HR) drop ≥20% after high frequency stimulation (HFS). The endpoint of inexistence of HR decrease at repeating HFS was achieved in 18 sites. No syncope attacked during 12 months and three tilt-table tests performed at 1, 6, and 12 months were negative. Extensive ablation on atrial endocardium for vagal denervation is suggested to be efficient in cardioinhibition type of VVS.

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http://dx.doi.org/10.1111/j.1540-8159.2011.03320.xDOI Listing

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