Packaging in dsRNA viruses.

Adv Exp Med Biol

Public Health Research Institute Center, UMDNJ - New Jersey Medical School, Newark, NJ 07103, USA.

Published: April 2012

Several families of viruses have segmented genomes with 3-12 chromosomes. They are capable of packaging these segments in a precise manner so that each virus particle contains one each of the genomic segments. The Cystoviridae are a family of bacteriophages that contain three genomic segments of dsRNA. During infection, the virus produces empty dodecahedral core particles that have the ability to specifically package plus strand transcripts of the genomic segments. The program of packaging makes use of the conformational changes in the surface of the particle as each transcript is packaged. The particles have complexes of a hexameric NTPase that serve as motors to bring the transcripts into the particle, and they have polymerase molecules in the interior that synthesize minus and plus strand copies of the genomic segments.

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-4614-0980-9_26DOI Listing

Publication Analysis

Top Keywords

genomic segments
16
segments
5
packaging dsrna
4
dsrna viruses
4
viruses families
4
families viruses
4
viruses segmented
4
segmented genomes
4
genomes 3-12
4
3-12 chromosomes
4

Similar Publications

Background: The Anopheles culicifacies complex is one of the most important malaria vectors in Southeast Asia and Southeastern Iran. Although the sibling species within this complex are morphologically indistinguishable, they differ significantly in their disease transmission potential, blood-feeding behaviour, and other biological traits. Cytogenetic and chromosomal studies have identified five sibling species within this complex: A, B, C, D, and E.

View Article and Find Full Text PDF

Background: Zinc finger homeodomain (ZF-HD) belongs to the plant-specific transcription factor (TF) family and is widely involved in plant growth, development and stress responses. Despite their importance, a comprehensive identification and analysis of ZF-HD genes in the soybean (Glycine max) genome and their possible roles under abiotic stress remain unexplored.

Results: In this study, 51 ZF-HD genes were identified in the soybean genome that were unevenly distributed on 17 chromosomes.

View Article and Find Full Text PDF

Estimating realized relatedness in free-ranging macaques by inferring identity-by-descent segments.

Proc Natl Acad Sci U S A

January 2025

Department of Primate Behavioral Ecology, Institute of Biology, Leipzig University, Leipzig 04103, Germany.

Biological relatedness is a key consideration in studies of behavior, population structure, and trait evolution. Except for parent-offspring dyads, pedigrees capture relatedness imperfectly. The number and length of identical-by-descent DNA segments (IBD) yield the most precise relatedness estimates.

View Article and Find Full Text PDF

Despite the recent surge of viral metagenomic studies, it remains a significant challenge to recover complete virus genomes from metagenomic data. The majority of viral contigs generated from de novo assembly programs are highly fragmented, presenting significant challenges to downstream analysis and inference. To address this issue, we have developed Virseqimprover, a computational pipeline that can extend assembled contigs to complete or nearly complete genomes while maintaining extension quality.

View Article and Find Full Text PDF

We present a comprehensive genetic investigation of Late Neolithic (LN) and Early Copper Age (ECA) populations living in the Carpathian Basin, leveraging whole genome data from 125 previously unreported individuals. Using population genetics, kinship analyses and the study of networks of identity-by-descent haplotype segment sharing, we elucidate the social and genetic dynamics of these communities between 4800-3900 cal BCE. Despite changes in settlement patterns, burial practices, and material culture, we document a high degree of genetic continuity.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!