Nanowire-based light-emitting devices require multi-quantum well heterostructures with high room temperature optical efficiencies. We demonstrate that such efficiencies can be attained through the use of ZnO/Zn((1-x))Mg(x)O core-shell quantum well heterostructures grown by metal organic vapor phase epitaxy. Varying the barrier Mg concentration from x = 0.15 to 0.3 leads to the formation of misfit induced dislocations in the multi-quantum wells. Correlatively, temperature dependent photoluminescence reveals that the radial well luminescence intensity decreases much less rapidly with increasing temperature for the lower Mg concentration. Indeed, about 54% of the 10 K intensity is retained at room temperature with x = 0.15, against 1% with x = 0.30. These results open the way to the realization of high optical efficiency nanowire-based light-emitting diodes.
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http://dx.doi.org/10.1088/0957-4484/23/8/085705 | DOI Listing |
J Fluoresc
January 2025
Department of Chemistry, Quaid-i-Azam University, Islamabad, 45320, Pakistan.
From synthesis to application, there are always certain interactions between the polar solvents and perovskite nanocrystals (NCs). To explain the effect of solvent polarity especially on the photoluminescence (PL) properties of NCs is highly desirable, especially for sensing applications. Herein We have synthesized the methylammonium lead mixed halides (MAPbClBr, where n = 0, 0.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Background: The detection and monitoring of Alzheimer's disease (AD) biomarkers in plasma are crucial for early diagnosis and prognosis. However, the stability of plasma AD biomarkers can be compromised by the degradation caused by endogenous proteases present in blood. The efficacy of protease inhibitors in mitigating this degradation is yet to be established.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Institute of Neuroscience and Physiology, The Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden; UCL Institute of Neurology, Queen Square, London, United Kingdom.
Background: Recent advancements in sample collection and storage methods, as well as biomarker measurement technologies, have made it possible to determine highly accurate biomarkers for Alzheimer's disease (AD) in regular plasma samples collected by venipuncture or as dried plasma spots.
Methods: A novel ultrasensitive biomarker measurement method called NUcleic acid Linked Immuno-Sandwich Assay (NULISA), which improves the sensitivity of traditional proximity ligation assays to attomolar level, by suppressing assay background via a dual capture and release mechanism, was evaluated against Single molecule array (Simoa) technology for AD biomarker measurement. Dried plasma spots were evaluated in relation to regularly collected EDTA plasma samples.
Angew Chem Int Ed Engl
January 2025
Key Laboratory of Advanced Energy Materials Chemistry, College of Chemistry, Weijin Road 94, 300071, Tianjin, CHINA.
Background: An advantage of blood-based biomarkers of Alzheimer's disease (AD) is that collection is easily repeatable and minimally invasive. Repeated biomarker measurements provide greater sensitivity for detecting within-person change, which in clinical trials can allow for reductions in sample sizes required to detect treatment effects and shorten trial periods. We validated Dried Blood Spots (DBS) as a novel matrix for measuring blood biomarkers of AD, as collection is easily repeatable, less burdensome for participants, and more economical than phlebotomy, and shipment and storage are simplified.
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