This is a case study of a 23 year old male diagnosed with Acanthamoeba keratitis. Initial misdiagnosis and inappropriate treatment lead to increased severity of the infection requiring surgical intervention. This case illustrates the complexity of Acanthamoeba keratitis infection, highlighting the diagnostic challenges which often begin with misdiagnosis and treatment, the role of the laboratory in providing confirmatory testing, and the relevance of patient knowledge related to contact lens wear and care.
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Sci Rep
January 2025
Department of Microbiology, Ajou University School of Medicine, Suwon, 16499, Republic of Korea.
J Microbiol Immunol Infect
January 2025
Department of Ophthalmology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Electronic address:
Purpose: This retrospective study aimed to investigate demographic characteristics, predisposing factors, and clinical outcomes in patients with parasitic keratitis.
Methods: Medical records of patients with molecularly confirmed Acanthamoeba or microsporidia, identified through corneal scraping specimens (collected between September 21, 2017, and June 27, 2023), were reviewed. Demographic data, clinical profiles, such as symptom duration before confirmed diagnosis, antiviral treatment pre-diagnosis, contact lens use, tap water and soil contamination, ocular trauma, and treatment regimens, were analyzed.
We present a case of mixed microbial keratitis in an otherwise healthy contact lens wearer. The microbes detected on microscopy included , , , and . and are well-recognised corneal pathogens, although is uncommon, and is extremely rare.
View Article and Find Full Text PDFMed Mycol Case Rep
March 2025
Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
A 42-year-old woman was referred to an emergency department. She had an unresponsive corneal ulcer that was initially diagnosed as virus keratitis. Later, the microbiological studies revealed fungal keratitis.
View Article and Find Full Text PDFJ Ophthalmic Inflamm Infect
January 2025
School of medicine, Shahid Sadoughi University of Medical sciences, Yazd, Iran.
Introduction: Infectious keratitis is a rare but devastating complication following photorefractive keratectomy (PRK) that may lead to visual impairment. This study assessed the clinical features, treatment strategies, and outcomes of post-PRK infectious keratitis.
Methods: This retrospective study was conducted on patients with post-PRK infectious keratitis presenting to Khalili Hospital, Shiraz, Iran, from June 2011 to March 2024.
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