AI Article Synopsis
- The study aimed to compare long-term outcomes of laparoscopic versus open complete mesocolic excision (CME) for colon cancer in 273 patients.
- No significant differences were found in margin lengths, lymph node counts, or recurrence/metastasis rates between the laparoscopic and open surgery groups after an average follow-up of 50 months.
- The overall and disease-free survival rates were similar between the two surgical approaches, suggesting that laparoscopic CME could be a standardized option for colon cancer treatment.
Article Abstract
Objective: To explore the differences in long-term outcomes between laparoscopic and open complete mesocolic excision(CME) for colon cancer.
Methods: A total of 273 patients with colon cancer who underwent CME at the Fujian Medical University Union Hospital from September 2000 to December 2008 were divided into laparoscopic(LP, n=147) and open(OP, n=126) groups in a non-random manner. The oncologic and long-term outcomes were compared.
Results: No significant differences were seen in the length of distal and proximal margin, and number of lymph nodes(all P>0.05). Median postoperative follow up was 50 months. Local regional recurrence rates (LP 6.1% vs. OP 7.9%) and distal metastasis rates(LP 23.8% vs. OP 16.7%) were similar between the two groups(all P>0.05). The 5-year overall survival rates (LP 69.4% vs. OP 74.0%, P=0.840) and 5-year disease-free survival rates(LP 68.5% vs. OP 70.9%, P=0.668) between the two groups were not statistically different.
Conclusions: Laparoscopic CME has the same oncologic clearance effects compared with open CME for colon cancer. It might become a new standardized surgery for colon cancer.
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