The tandem Crabbé homologation-radical rearrangement of terminal enediynes leads, in a one-pot procedure, to the enantioselective synthesis of six- and seven-membered ring α-aminoesters bearing a quaternary stereocenter based on the phenomenon of memory of chirality.
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http://dx.doi.org/10.1039/c2cc17830c | DOI Listing |
Chem Commun (Camb)
March 2012
Institut de Chimie Radicalaire (ICR), UMR 7273, Aix-Marseille Université, Faculté de St Jérôme, Avenue Escadrille Normandie-Niemen, 13397 Marseille Cedex 20, France.
The tandem Crabbé homologation-radical rearrangement of terminal enediynes leads, in a one-pot procedure, to the enantioselective synthesis of six- and seven-membered ring α-aminoesters bearing a quaternary stereocenter based on the phenomenon of memory of chirality.
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