AI Article Synopsis
- Osteopetrosis is a rare bone disease that leads to excessively hard and brittle bones due to impaired bone resorption by osteoclasts, causing frequent fractures and risk of osteoarthritis.
- Total knee arthroplasty is commonly used to treat knee issues in these patients, but it can be complicated because of the unusually dense bone structures in the femur and tibia.
- The case presented involved a patient with osteopetrosis receiving total knee arthroplasty using patient-specific instruments, which reduces the need for invasive techniques and may lessen surgery time and complications.
Article Abstract
Osteopetrosis is an uncommon endocrine disease characterized by defective osteoclast resorption of bones. This causes a hard, sclerotic, and brittle bone throughout the skeleton. Fractures and unforgiving subchondral bone are common in this condition, both of which can lead to osteoarthritis. Total knee arthroplasty is often the treatment of choice but presents challenges due to the hard and sclerotic bone present throughout the metaphysis and diaphysis of the femur and the tibia. We present a case of knee osteoarthritis in a patient with osteopetrosis who underwent total knee arthroplasty using patient-specific instrumentation. This technique eliminates intramedullary alignment and minimizes drilling, reaming, and saw passes, making it attractive in the setting of diseases such as osteopetrosis to decrease operative time and potential complications.
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