Within the last few decades, outcomes research, and in particular quality of life (QoL) outcomes research, has become integrated into clinical and research practices. QoL outcomes are important to dermatology, because many diseases carry significant psychosocial burdens and morbidity from appearance and symptoms with few cases of mortality. In this article, the authors discuss the future directions in QoL. Important areas are the determination, clinical significance and interpretation of measured QoL values. Additionally, the development of proxies for preference-based QoL measures and modules for health status QoL measures are discussed.
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http://dx.doi.org/10.1016/j.det.2011.11.005 | DOI Listing |
NPJ Digit Med
January 2025
Department of Plastic and Reconstructive Surgery, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
This systematic review explores machine learning (ML) applications in surgical motion analysis using non-optical motion tracking systems (NOMTS), alone or with optical methods. It investigates objectives, experimental designs, model effectiveness, and future research directions. From 3632 records, 84 studies were included, with Artificial Neural Networks (38%) and Support Vector Machines (11%) being the most common ML models.
View Article and Find Full Text PDFMedicine (Baltimore)
November 2024
Department of Infectious Diseases, Nantong Clinical Medical College of Integrated Traditional Chinese and Western Medicine of Nanjing University of Chinese Medicine, Nantong Third People's Hospital, Affiliated Nantong Hospital 3 of Nantong University, Nantong, China.
Background: To investigate global trends and current research on post-traumatic osteoarthritis (PTOA) from 2010 to 2024 using bibliometric and visualization techniques.
Methods: A bibliometric analysis was conducted using data from the Web of Science Core Collection. The study examined publication trends, author contributions, institutional collaborations, keyword co-occurrence, and citation patterns, employing CiteSpace software to analyze key metrics such as publication frequency, centrality, and clustering.
Sci Total Environ
January 2025
Department of Biological Sciences, University of Illinois at Chicago, Chicago, IL 60607, USA.
Changes in winter precipitation accompanying emerging climate trends lead to a major carbon-climate feedback from Arctic tundra. However, the mechanisms driving the direction, magnitude, and form (CO and CH) of C fluxes and derived climate forcing (i.e.
View Article and Find Full Text PDFTherapie
December 2024
VIM Suresnes, UMR_0892, hôpital Foch, université Paris-Saclay, 92150 Suresnes, France.
Over the past decade, new in vitro biological models have emerged which can reproduce certain characteristics of human physiology and pathologies. From organoids to organs-on-chips, these new technologies are currently revolutionizing the entire chain of research and development in pharmacology. All stakeholders are thus involved, from academic laboratories to pharmaceutical companies, start-ups, and assessment agencies.
View Article and Find Full Text PDFJ R Soc Interface
January 2025
Mathematical Institute, University of Oxford, Oxford, UK.
Random walks and related spatial stochastic models have been used in a range of application areas, including animal and plant ecology, infectious disease epidemiology, developmental biology, wound healing and oncology. Classical random walk models assume that all individuals in a population behave independently, ignoring local physical and biological interactions. This assumption simplifies the mathematical description of the population considerably, enabling continuum-limit descriptions to be derived and used in model analysis and fitting.
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