Objective: The aim was to evaluate the effect of honey dressing and silver sulfadiazene (SSD) dressing on wound healing in burn patients.
Materials And Methods: We retrospectively reviewed the records of 108 patients (14-68 years of age), with first and second degree burns of less than 50% of the total body surface area admitted to our institution, over a period of 5 years (2004-2008). Fifty-one patients were treated with honey dressings and 57 with SSD. Time elapsed since burn, site, percentage, degree and depth of burns, results of culture sensitivity at various time intervals, duration of healing, formation of post-treatment hypertrophic scar, and/or contracture were recorded and analyzed.
Results: The average duration of healing was 18.16 and 32.68 days for the honey and SSD group, respectively. Wounds of all patients reporting within 1 h of burns became sterile with the honey dressing in less than 7 days while there was none with SSD. All wounds treated with honey became sterile within 21 days while for SSD-treated wounds, this figure was 36.5%. A complete outcome was seen in 81% of all patients in the "honey group" while in only 37% patients in the "SSD group."
Conclusion: Honey dressings make the wounds sterile in less time, enhance healing, and have a better outcome in terms of hypertropic scars and postburn contractures, as compared to SSD dressings.
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http://dx.doi.org/10.4103/0974-2077.91249 | DOI Listing |
Dermatol Reports
November 2024
Plastic Surgery Unit, Department of Neuroscience, University of Padua.
Keratitis-ichthyosis-deafness syndrome (KID) is a rare genetic disorder characterized by the triad of hyperkeratosis, ichthyosis, and congenital prelingual sensorineural deafness, with less than 100 cases described in the literature. In addition to many other extra-cutaneous manifestations, these patients are burdened by two principal increased risk factors involving the skin: the risk of developing infections and the risk of developing malignant skin tumors, especially Squamous Cell Carcinoma and Trichilemmal tumors. We present the case of a 7-year-old girl with a unique genetic variant described to date, who developed 4 dyskeratotic neoformation.
View Article and Find Full Text PDFDermatologie (Heidelb)
December 2024
Colentina Klinik, Dermatologie 2, "Carol Davila" Universität für Medizin und Pharmazie, Bukarest, Rumänien.
Treatment of diabetic foot is challenging due to the complex pathophysiological mechanisms, various clinical manifestations, severe complications with considerable impairment of quality of life, and the need for special, individualized treatment strategies. Particularly in the case of diabetic foot ulcers, conventional therapies are not always effective, so new treatment strategies are needed. This review aims to present alternative therapies with current efficacy data for diabetic foot ulcers that may be suitable for treatment-refractory ulcers.
View Article and Find Full Text PDFACS Appl Bio Mater
December 2024
Caspian Faculty of Engineering, College of Engineering, University of Tehran, Rezvanshar, Guilan 43861-91836, Iran.
A promising approach for wound treatment is using multilayer wound dressings that offer multifunctional properties. In this study, a bilayered electrospun/hydrogel gelatin-based scaffold integrated with honey and curcumin was developed to treat wounds under an in vivo study. The first layer consisted of an enzymatic cross-linked gelatin hydrogel containing honey and curcumin, which gelatin/PCL nanofibers reinforced.
View Article and Find Full Text PDFACS Appl Bio Mater
December 2024
Department of Pharmaceutical Sciences and Technology, Birla Institute of Technology, Mesra, Ranchi 835215, Jharkhand, India.
The present study aims to formulate a stimuli-responsive hydrogel system to codeliver acacia honey and glycyrrhizic acid for topical application that will aid in absorbing wound exudates, control microbial infestation, and produce angiogenic and antioxidant effects to accelerate wound healing. Therefore, both the natural active constituents were incorporated within an hydrogel composed of poloxamer and hydroxypropyl methylcellulose (HPMC), where the concentrations of the polymers were optimized using Design-Expert software considering optimum values of the dependent variables, gelation temperature (34-37 °C), gelation time (<10 min), and the viscosity (2000-3500 cPs). The optimized formulation showed improved physicochemical properties such as mucoadhesiveness, porosity, swelling, and spreadability, which makes it suitable for wound application.
View Article and Find Full Text PDFMed Oral Patol Oral Cir Bucal
January 2025
Mashhad dental school Mashhad university of medical sciences university campus P.O. Box: 9178613111, Mashhad, Iran
Background: To evaluate the efficacy of a novel topical dressing (composed of triamcinolone, ground Dianthus caryophyllus, eugenol, honey, and Iris germanica) for alveolar osteitis (dry socket) against Alvogyl® (composed of eugenol, butamben, and iodoform).
Material And Methods: In a randomized parallel-armed clinical trial at Mashhad Dental School's Department of Oral and Maxillofacial Surgery, 36 patients with alveolar osteitis were randomly allocated into two groups according to the inclusion criteria (n=18), using sealed envelopes: one receiving a novel topical dressing and the other receiving Alvogyl®. Post-treatment pain was assessed using a visual analog scale immediately after the procedure and at 30 and 60 minutes, 24, 48, 72, and 96 hours, and one week later, as well as the frequency of dressing applications and analgesic usage.
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