Wnt signaling: the β-cat(enin)'s meow.

Genes Dev

Stem Cell Program, Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, California 92093, USA.

Published: January 2012

In a study in the December 15, 2011, issue of Genes & Development, Valenta and colleagues (pp. 2631-2643) constructed a series of β-catenin mutants that allowed them to separate β-catenin's activity as a mediator of Wnt signaling from its activity as cell adhesion component. In doing so, they uncovered some surprising properties of Wnt signaling.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273833PMC
http://dx.doi.org/10.1101/gad.185280.111DOI Listing

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