Redundant pathways of sunscreen biosynthesis in a cyanobacterium.

Chembiochem

Institute of Pharmaceutical Science, King's College London, 150 Stamford Street, London SE1 9NH, UK.

Published: March 2012

Route of the sun block: according to empirical evidence, sun-screening mycosporine-like amino acids (MAAs) in Eukarya originate from the shikimic acid pathway, whereas in cyanobacteria, biosynthesis of the MAA shinorine reportedly occurs through the pentose phosphate pathway. However, gene deletion shows that the cyanobacterium Anabaena variabilis ATCC 29143 does not biosynthesise shinorine exclusively by this route.

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Source
http://dx.doi.org/10.1002/cbic.201100737DOI Listing

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