Microgeodic disease, similar to chilblains (pernio), is characterized by painful, erythematous swelling, as well as small, punched-out erosions found in affected phalanges. Although they share a similar appearance and proposed pathogenesis, chilblains has rarely been diagnosed in children with microgeodic disease, and in those cases has not been confirmed on skin biopsy. This article details a child in Connecticut diagnosed during the winter with chilblains and microgeodic disease of his toe, as supported by biopsy and imaging. These findings further indicate that the two diseases are interrelated, imply a similar pathogenesis, and lead us to suggest similar treatment for problematic forms of both diseases.
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http://dx.doi.org/10.1111/j.1525-1470.2011.01665.x | DOI Listing |
Skeletal Radiol
November 2024
Clementine Churchill Hospital, Harrow, England.
We present the clinical and radiological characteristics of phalangeal microgeodic syndrome in a cluster of five children during the second peak of COVID-19 pandemic in the UK. Each child presented with phalangeal swelling and erythema, prompting a comprehensive multi-disciplinary team review to analyse the clinical presentation, blood test results and imaging. The cohort's average age was 14.
View Article and Find Full Text PDFZ Rheumatol
May 2024
Hospital Privado de Gaia Trofa Saúde, Rua Fernão de Magalhães, n°2, Fração E 4400-629, Vila Nova de Gaia, Portugal.
Phalangeal microgeodic syndrome (PMS) is a rare osteolytic disorder of unknown etiology that typically affects children up to 15 years old during colder months. Transient peripheral circulatory impairment probably underlines its pathogenesis. Conservative treatment with eviction of cold exposure is often successful.
View Article and Find Full Text PDFGeriatr Gerontol Int
November 2023
Department of General Internal Medicine, Kobe City Medical Center General Hospital, Kobe, Japan.
J Clin Imaging Sci
December 2022
Department of Radiology, Watford General Hospital, Watford, Hertfordshire, United Kingdom.
Phalangeal microgeodic syndrome (PMS) is a rare rheumatological disease affecting children strongly associated with cold weather. It is considered to be benign and self-limiting, with most cases resolving in warmer months, and no studies have investigated its association to autoantibodies or viral infection. In this peculiar case, a 12-year-old child with the previous COVID-19 infection developed PMS that did not improve in the warm weather and, subsequently, Raynaud's phenomenon and facial rash.
View Article and Find Full Text PDFBMJ Case Rep
August 2022
General Paediatrics, The Royal Children's Hospital, Parkville, Victoria, Australia.
We describe an infant presenting with intermittent discolouration and swelling of her fingers and toes occurring with changes in ambient temperature. Extensive investigations revealed raised inflammatory markers as well as sclerotic lesions within the phalanges and diffuse marrow oedema. Infectious and inflammatory causes were considered and excluded based on the clinical presentation and investigation findings.
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