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Overcoming missed diagnoses of primary central nervous system Lymphoma-The key role of cerebrospinal fluid cytology: a case report.
Diagn Pathol
March 2025
Department of Laboratory Medicine, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou, 310006, China.
Background: Central nervous system (CNS) involvement in diffuse large B-cell lymphoma (DLBCL) is relatively rare, occurring at a rate of approximately 5%. Primary CNS lymphoma (CNS-DLBCL), a subtype of DLBCL, is rare clinically but highly malignant and invasive. Its atypical clinical symptoms and imaging features contribute to a high rate of misdiagnosis and a poor prognosis.
View Article and Find Full Text PDFThe asthma diagnosis jigsaw puzzle: an adaptable teaching concept to facilitate the diagnosis of asthma in adults and children presenting to primary care.
NPJ Prim Care Respir Med
March 2025
The International Primary Care Respiratory Group, Larbert, UK.
The asthma diagnosis jigsaw puzzle is a clinical practice and teaching concept conceived in clinical practice and refined through an expert multidisciplinary consensus process by academics and clinicians with an interest in primary respiratory care. The concept incorporates guidance to facilitate the effective diagnosis of adults or children with asthma in primary care where misdiagnosis is common. The jigsaw puzzle metaphor teaches a problem-solving approach to diagnosis, introducing the concept of diagnosis over time and in no particular sequence.
View Article and Find Full Text PDFA diagnostic and therapeutically challenging presentation of unicentric mesenteric Castleman disease: A case report.
Exp Ther Med
April 2025
Department of Science and Education, Affiliated Huishan Hospital of Xinglin College, Nantong University, Wuxi, Jiangsu 214000, P.R. China.
Castleman disease (CD) is a rare lymphoproliferative disorder primarily manifesting as either Multicentric CD (MCD) or Unicentric CD (UCD), with Unicentric Mesenteric CD (UMCD) representing a less common subtype within the UCD category. The present study presented an encounter with a 29-year-old male patient afflicted by UMCD, presenting with significant morbidity attributed to a sizable mesenteric mass. The diagnostic and therapeutic management of this condition posed notable challenges.
View Article and Find Full Text PDFAim: Complete mesocolic excision (CME) for colon cancer has been associated with improved oncological outcomes but requires a detailed understanding of complex mesenteric vasculature. Three-dimensional (3D) reconstructed models derived from patient imaging could enhance preoperative anatomical comprehension, enabling safer, precision CME.
Methods: In this two-phase, blinded, crossover study, four expert CME surgeons evaluated mesenteric vascular anatomy on CT scans and 3D models.
Gossypiboma-induced ileal obstruction following cholecystectomy: A case report and literature review.
Int J Surg Case Rep
March 2025
Department of General Surgery, Jamhuriat Hospital, Kabul, Afghanistan.
Introduction: Gossypiboma, the retention of surgical material in the body post-surgery, is a rare but serious complication often underreported due to legal and reputational concerns. It commonly occurs after abdominal surgeries, with presentations ranging from abscess formation to intestinal obstruction.
Presentation Of Case: An 18-year-old girl presented with abdominal pain and distention, along with vomiting for six weeks after cholecystectomy.
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