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Renal Clear Cell Carcinoma Masquerading As Brain Arteriovenous Malformation: A Case Report and Review of the Literature.
Cureus
December 2024
Neurosurgery, Southmead Hospital, North Bristol NHS, Bristol, GBR.
Cerebral arteriovenous malformations (AVMs) are tangles of abnormal vessels with early arteriovenous (AV) shunting that can lead to intracerebral hemorrhage, seizures, neurologic deficit, or headache. To date, only a few cases of carcinomas metastasizing to pre-existing cerebral AVMs have been reported in the literature. However, renal clear cell carcinoma (RCC) brain metastases that exhibit early AV shunting, where AVM pathology is not present, are extremely rare.
View Article and Find Full Text PDFPostpartum Hellp Syndrome Associated With Posterior Reversible Encephalopathy Syndrome.
Eur J Case Rep Intern Med
December 2024
Critical Care, Intensive Care Unit, Centro Hospitalar Universitário de Santo António, Porto, Portugal.
Unlabelled: Haemolysis, elevated liver enzymes and low platelets (HELLP) syndrome is a poorly understood, life-threatening multisystemic condition related to pregnancy with a rapid onset, typically observed in patients with severe pre-eclampsia. Various mechanisms may lead to diffuse endothelial damage associated with HELLP and possible brain involvement. A comprehensive review of PubMed, Embase and Cochrane databases was conducted to examine the clinical, laboratory and radiological features associated with postpartum HELLP syndrome, particularly its potential association with posterior reversible encephalopathy syndrome (PRES).
View Article and Find Full Text PDFAn analysis on role of iron deficiency in febrile seizure among children in 6 months to 5 years: A case-control study.
J Family Med Prim Care
December 2024
Department of Paediatrics, Sri Ramachandra Institute of Higher Education and Research, Tamil Nadu, India.
Background For The Study: This study looks into the relationship between febrile seizures in children between the ages of 6 months to 5 years who suffer from iron insufficiency. Febrile seizures, which are common in early life, are associated with abrupt temperature increases, and iron deficiency impacts neurological development in young infants. Understanding this relationship would lead to interventions that mitigate febrile seizure impact.
View Article and Find Full Text PDFA Self-Supporting Flexible Electrode for Tracking and Reversible Quantification of Mg2+ and Ca2+ in the Brains of Freely Behaving Animal.
Angew Chem Int Ed Engl
January 2025
East China Normal University, Dept. of Chemistry, Dongchuan Road 500, 200062, Shanghai, CHINA.
Monitoring dynamic neurochemical signals in the brain of free-moving animals remains great challenging in biocompatibility and direct implantation capability of current electrodes. Here we created a self-supporting polymer-based flexible microelectrode (rGPF) with sufficient bending stiffness for direct brain implantation without extra devices, but demonstrating low Young's modulus with remarkable biocompatibility and minimal position shifts. Meanwhile, screening by density functional theory (DFT) calculation, we designed and synthesized specific ligands targeting Mg2+ and Ca2+, and constructed Mg-E and Ca-E sensors with high selectivity, good reversibility, and fast response time, successfully monitoring Mg2+ and Ca2+ in vivo up to 90 days.
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