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Background: Weight-based and energy-based formulas are used to estimate the water requirements of patients receiving nutrition support, yet these formulas have not been validated nor quantitatively compared with one another. The objective of this study was to determine if there was agreement among commonly used formulas for estimating water requirements.
Design: This cross-sectional survey design was from the continuous National Health and Nutrition Examination Survey 1999-2004. To determine estimated water requirements for each participant, 2 weight-based formulas were used (30 mL/kg body weight and an adjusted body weight formula) and 3 energy-based formulas based on 1 mL/kcal (energy needs estimated by the Harris Benedict, Mifflin St Jeor, and National Research Council equations). Simple linear regression was performed between each pair of formulas to determine correlations. The regression line was then compared to the line of equality to determine agreement between pairs.
Results: Although the 5 formulas were strongly correlated to each other (|r| > 0.7), they demonstrated poor agreement with one another with significant differences when the regression line was compared to the line of equality.
Conclusions: Current formulas that estimate the water requirements of patients receiving enteral nutrition and parenteral nutrition all compute a dissimilar quantity of water. The consequences of these estimates could result in major differences in water intake recommendations and prescriptions between patients or in the same patient, thus suggesting a need for improved standardization of practice for estimating water requirements in clinical practice.
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http://dx.doi.org/10.1177/0148607111416484 | DOI Listing |
J Control Release
December 2024
Université Paris-Saclay, CEA, CNRS, Inserm, BioMaps, SHFJ, Orsay 91401, France.. Electronic address:
Mertansine (DM1), a potent tumor-killing maytansinoid, requires conjugation to antibodies or incorporation into nanocarriers due to its high toxicity. However, these carriers often result in undesirable biodistribution, leading to rapid and long-term accumulation in the kidneys or liver and potentially increased toxicity. To overcome this limitation, we used the hydrophilic, biocompatible, and stealth properties of polyacrylamide (PAAm) as a scaffold to develop water-soluble PAAm-DM1 polymer prodrugs, leveraging PAAm's previous success in delivering paclitaxel via subcutaneous administration.
View Article and Find Full Text PDFJ Acoust Soc Am
December 2024
Department of Applied Ocean Physics and Engineering, Woods Hole Oceanographic Institution, Woods Hole, Massachusetts 02543, USA.
This article presents a spatial environmental inversion scheme using broadband impulse signals with deep learning (DL) to model a single spatially-varying sediment layer over a fixed basement. The method is applied to data from the Seabed Characterization Experiment 2022 (SBCEX22) in the New England Mud-Patch (NEMP). Signal Underwater Sound (SUS) explosive charges generated impulsive signals recorded by a distributed array of bottom-moored hydrophones.
View Article and Find Full Text PDFEcol Evol
December 2024
First Zoological Department Vienna Museum of Natural History Vienna Austria.
The Dinaric Karst extends along the Adriatic coast of the Western Balkan Peninsula and is home to a group of "karst minnows" of the genera , , and , which have adapted to the highly variable water conditions in the karst by spending up to several months underground, but require surface habitats for spawning, defining them as substygophiles. The three species of the genus , , , and , are defined by restricted ranges, making them vulnerable to pollution and extended draughts caused by the climate change. In this study, the phylogeny of Leusciscinae was reconstructed using 15 and one , one , and one complete mitochondrial genomes and the position of the genus within the subfamily as sister species to the clade was confirmed.
View Article and Find Full Text PDFEcol Evol
December 2024
Faculty of Agriculture, Forest and Food Engineering Yibin University Yibin Sichuan China.
Habitat selection in animals results from a careful balance of individual requirements, environmental conditions, and ecological disturbances. Preferences can vary across sexes and ages due to differences in survival and reproductive priorities. Despite this variability, most studies have traditionally focused on isolated aspects of either sex or age-related differences in habitat selection, rather than considering a comprehensive range of influencing factors.
View Article and Find Full Text PDFHeliyon
December 2024
Chemistry Department, Faculty of Science, Cairo University, Giza, 12613, Egypt.
The extensive use of azo dyes in textile and pharmaceutical industries pose significant environmental and health risks. This problem requires to be tackled forthwith through a cheap, environmentally friendly and viable approach to mitigate water pollution. In this context, the green synthesis method was used for synthesis of ZnO NPs.
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