AI Article Synopsis
- A comprehensive explanation for heart failure has been difficult to establish, but advancements in understanding its mechanisms have led to better treatment options.
- The incidence of heart failure during non-cardiac surgeries is around 1%, which can lead to serious cardiovascular complications.
- This article aims to explore the clinical evidence for the use of venodilators in managing heart failure in surgical patients.
Article Abstract
A unifying hypothesis which satisfactorily explains the clinical syndrome of heart failure has proved elusive. A deeper understanding of the underlying pathophysiology has led to the development of more complex models and, as a result, the evolution of new treatment strategies. In patients undergoing non-cardiac surgery, perioperative heart failure has an incidence of approximately 1% and is a predictor of major adverse cardiovascular events. Although vasodilators undoubtedly play a major role in the management of patients with heart failure, the relative importance of venodilatation remains unclear. The purpose of this article is to discuss the clinical evidence supporting the use of drugs with venodilating properties in surgical patients with heart failure.
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| http://dx.doi.org/10.1097/EJA.0b013e32835016be | DOI Listing |
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