Background: Ovarian pregnancy is a rare occurrence. Normally it ends spontaneously in the first trimester. However, it can turn into a life-threatening condition if it ruptures, leading to hemoperitoneum and hypovolemic shock. Diagnosis usually is made with high-resolution transvaginal ultrasonography, and laparoscopic treatment follows.
Case: We report on a case of ovarian pregnancy seen in the southeast of Madagascar. Laparotomy revealed the presence of a fully developed, mummified fetus in the right ovary. Surprisingly, the ovary capsule had not ruptured and the patient had no complaints or signs of intra-abdominal bleeding.
Conclusion: In rare cases, an aborted ovarian pregnancy can persist for years, producing no symptoms except abdominal swelling.
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http://dx.doi.org/10.1097/AOG.0b013e318236f00e | DOI Listing |
Aust N Z J Obstet Gynaecol
January 2025
Reproductive Services Unit, The Royal Women's Hospital, Parkville, Australia.
Background: Modern assisted reproductive technology (ART), including pre-implantation genetic testing for aneuploidy (PGT-A), has opened new avenues in understanding early embryonic events and has simultaneously raised questions about the impact of ART itself on sex ratios.
Aims: The primary aim was to investigate whether patient demographic characteristics, ovarian stimulation protocols or laboratory characteristics in ART influence sex ratios. The secondary aim was to relate the blastocyst sex ratio (BSR) to the corresponding secondary sex ratio (SSR) in our patient cohort.
Life Sci
January 2025
Studies of the Physiopathology of the ovary laboratory, Institute of Biology and Experimental Medicine (IBYME) - National Scientific and Technical Research Council (CONICET), Vuelta de Obligado 2490, C1428ADL Buenos Aires, Argentina. Electronic address:
Aims: Metformin has shown beneficial effects on reproduction in women. However, its use during pregnancy remains controversial, as metformin can cross the placenta. Most studies have focused on the metabolic impact on the offspring of treated mothers, with limited information regarding its reproductive effects.
View Article and Find Full Text PDFAging (Albany NY)
January 2025
School of Medicine, National University of La Plata (UNLP), La Plata, Argentina.
In middle-aged (MA) female rats, we have demonstrated that intrahypothalamic gene therapy for insulin-like growth factor-I (IGF-I) extends the regular cyclicity of the animals beyond 10 months (the age at which MA rats stop ovulating). Here, we implemented long-term OSKM gene therapy in the hypothalamus of young female rats. The main goal was to extend fertility in the treated animals.
View Article and Find Full Text PDFNucl Med Biol
January 2025
Central Research Laboratory, Hamamatsu Photonics K.K., Hamana, Hamamatsu, Shizuoka 434-8601, Japan.
Background: The ovary is an important female organ not only for pregnancy but also for the regulation of life activities via hormone release. Ovarian function is measured by blood hormone levels, but the hormone level reflects only the ovarian reserve and no other essential ovarian functions, such as nurturing and expelling follicles. Ovarian fibrosis is related to essential ovarian function; however, the existing methods for evaluating fibrosis are invasive.
View Article and Find Full Text PDFAnimal
December 2024
Alta Genetics Brasil Ltda., Uberaba 38055-010, Brazil.
Timed artificial insemination (TAI) is a technology widely used in cattle production based on controlling ovarian follicular growth. This study analyzed a large database aiming to determine the influence of several intrinsic and extrinsic female factors, as well as their interactions to determine risk factors and produce prediction ability in beef cattle. A total of 1 832 999 TAIs conducted on 2 002 farms across South American countries were considered for the analysis, including 15 main fixed effects or interactions in the statistical model, in addition to five random effects.
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