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Changes in apoptosis and cell proliferation in human pineal gland during aging. | LitMetric
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Changes in apoptosis and cell proliferation in human pineal gland during aging.

V O Polyakova N S Linkova S A Pichugin

Bull Exp Biol Med

Saint-Petersburg Institute of Bioregulation and Gerontology, North-West Division, Russian Academy of Medical Sciences, Russia.

Published: February 2011

Immunohistochemical analysis of the expression of proapoptotic protein P53 and proliferation protein Ki-67 in human pineal gland showed that in people over 60 years pinealocyte proliferation is virtually absent. Moreover, pinealocyte apoptosis is more pronounced in elderly, whereas in senile and long-living individuals its intensity decreases.

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http://dx.doi.org/10.1007/s10517-011-1170-xDOI Listing

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