Researchers have identified an association between baseline γ-glutamyltransferase (GGT) and prehypertension. However, data from China are limited. A cross-sectional study was performed among 2,205 subjects from Heilongjiang Province in China. Multiple logistic regression analyses revealed a significant association between baseline GGT and prehypertension [1.59, 95% confidence interval (CI), 1.18-2.16], comparing quartile 4 to quartile 1. Subgroup analyses showed a stronger association between GGT and prehypertension in Koreans; men, current alcohol drinkers and subjects with pre-diabetes. Receiver operating characteristics (ROC) analysis demonstrated that when GGT was higher than 20 U/l, the risk of developing prehypertension increased. Serum GGT is used as a biochemical liver test, but our findings suggest that baseline values may also predict prehypertension in Chinese.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493114 | PMC |
| http://dx.doi.org/10.3892/mmr.2012.761 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Serum γ-glutamyltransferase levels and obesity status changes the risk of prehypertension in Chinese adults.
Prev Med Rep
July 2024
Department of Endocrinology, The Second People's Hospital of Lianyungang, Jiangsu, China.
Objective: It's well known that γ-Glutamyltransferase (γ-GGT) and obesity plays an important role in the development of preHT. However, the effect of γ-GGT on preHT in populations with different obesity status remains unclear.
Methods: From February 2014 to January 2018, a total of 20,368 participants were enrolled in this study after excluding those with hypertension and liver diseases.
The relationship between liver enzymes, prehypertension and hypertension in the Azar cohort population.
BMC Cardiovasc Disord
June 2024
Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
Background: The incidence of hypertension (HTN) as a worldwide health problem is rising rapidly. Early identification and management of pre-HTN before HTN development can help reduce its related complications. We evaluated the relationship between liver enzymes levels and pre-HTN/HTN in the Azar cohort population.
View Article and Find Full Text PDFGamma-glutamyltransferase, arterial remodeling and prehypertension in a healthy population at low cardiometabolic risk.
J Hum Hypertens
April 2021
Department of Surgical, Medical Molecular Pathology and Critical Care Medicine, University of Pisa, Via Savi 10, 56126, Pisa, Italy.
Plasma gamma-glutamyltransferase (GGT) was suggested to reflect the level of systemic oxidative stress. Oxidative stress induces changes in arterial structure and function and contributes to the development of hypertension. Therefore, GGT may be associated with arterial remodeling and blood pressure (BP) increment, even in absence of disease.
View Article and Find Full Text PDFBiomarkers of nondipper hypertension in prehypertensive and hypertensive patients.
Biomark Med
April 2019
Ankara Numune Education and Research Hospital, University of Health Sciences, Ankara, Turkey Istanbul Umraniye Education and Research Hospital, University of Health Sciences, Istanbul, Turkey.
The aim of this study was to evaluate the relation of gamma glutamyl transferase (GGT), neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) with nondipper hypertension. This study included a total of 409 patients. Patients were grouped into hypertension, prehypertension and normotensive groups, according to their clinical blood pressure.
View Article and Find Full Text PDFRelationship between serum gamma-glutamyltransferase levels and prehypertension in Chinese adults: the cardiometabolic risk in Chinese study.
J Clin Hypertens (Greenwich)
October 2014
Xuzhou Medical College, Xuzhou, China.
The authors aimed to investigate the relationship between serum gamma-glutamyltransferase (GGT) and prehypertension, as well as the modification of other metabolic risk factors in a large cohort of Chinese individuals. The data were collected via a community-based health examination survey in central China. Blood pressure, body mass index (BMI), and levels of GGT, fasting blood glucose, aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lipid indicators were measured.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!