Objectives: The aim of this study was to evaluate the oxidative status in patient with Brucella canis (B. canis) and healthy controls by measurement of total antioxidant capacity (TAC) and total oxidant capacity (TOS), and calculation of oxidative stress index (OSI).
Design And Methods: Six patients with B. canis and 6 healthy control subjects were included in this study. Diagnosis of B. canis was made by rapid slide agglutination test (RSAT) and Modified Plate Agglutination Test (MPAT). The serum samples of B. canis positive patients and controls were used for measurement of TAC and TOS levels.
Results: The TOS and OSI index were significantly higher in brucellosis positive patients than control group (p<0.001 and p<0.0001, respectively), while TAC level was found similar in patient and control groups.
Conclusion: Findings of this study have shown that B. canis generate low TOS and OSI index in man compared with smooth Brucella species infection. This difference may help to provide understanding about the pathogenesis of B. canis infection in man.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.clinbiochem.2011.12.028 | DOI Listing |
Front Cell Infect Microbiol
January 2025
The First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.
Objective: To establish a rapid detection method for canine using recombinase-aided amplification (RAA) technology.
Methods: The outer membrane protein 25 gene fragment (Omp25) of canis was targeted. Primers and fluorescent probes were designed and synthesized, and recombinant plasmids were constructed as standards.
Eur J Public Health
January 2025
National Reference Laboratory for Plague, Tularemia and Q Fever, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran, Akanlu, Kabudar-Ahang, Hamadan, Iran.
The purpose of this study was to assess the prevalence of zoonotic bacteria, including Coxiella burnetii, Bartonella spp., Rickettsia spp., Brucella spp.
View Article and Find Full Text PDFActa Trop
January 2025
Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahid Bahonar University of Kerman, Kerman, Iran.
Introduction: Brucellosis is still a significant emerging threat to public health, as it can infect humans, wild, domestic animals, and livestock. Hence, the current study aims to determine the frequency of canine brucellosis (CB), its relationship with clinical findings and reproductive disorders in kennel and farm dogs, and its importance on public health.
Materials And Methods: From January 2022 to December 2023, a total of 150 blood samples were taken from 100 adult dogs in breeding kennels and 50 shepherd dogs in breeding farms in Kerman, Iran.
Front Vet Sci
November 2024
Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, Italy.
Introduction: Shelters for stray dogs and cats deserve careful monitoring for zoonotic risk, as they represent a crucial point for prevention and control of infection spread. Data sorting to prioritize zoonotic agents in a geographic area need constant updating, but no regular official programs are ongoing, to allow an efficient risk survey for these animal species. This study aimed to conduct a comprehensive investigation of the prevalence of certain known, potential and emerging zoonoses within the framework of the routine monitoring of dog and cat shelters in North-East Italy.
View Article and Find Full Text PDFComp Immunol Microbiol Infect Dis
January 2025
Department of Microbiology, Faculty of Veterinary Medicine, Harran University, Şanlıurfa, Turkey. Electronic address:
Brucella canis and smooth Brucella species infections have been reported in dogs globally. In endemic countries such as Türkiye, dogs can be infected with both species. The exact incidence of canine brucellosis in Türkiye is unknown.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!