We report the use of sugammadex to reverse a rocuronium block in a man who had received a kidney transplant 4 years earlier. The patient was admitted for gastric non-Hodgkins lymphoma and bleeding that required surgery. Arterial hypertension, tachycardia, and frequent ventricular extrasystoles were detected. Anesthetic induction was accomplished with propofol, fentanyl, and rocuronium; intubation was uneventful. We monitored pulse oximetry, capnography, heart rate, electrocardiography, arterial pressure (invasive), cardiac output, end-systolic volume, bispectral index, temperature, and neuromuscular function. Anesthesia was maintained with an infusion of propofol, fentanyl, and rocuronium guided by train-of-four (TOF) ratio. Total diuresis was 1100 mL. The operation lasted 4.5 hours. Recovery of neuromuscular response was spontaneous until the second TOF twitch, after which we injected 2 mg/kg of sugammadex. A TOF ratio of 0.94 was recorded 158 seconds after injection of the reversal agent. The patient was extubated without complications. Sugammadex can be used in patients with a transplanted kidney, provided the glomerular filtration rate has recovered sufficiently to allow full excretion of the sugammadex-rocuronium complex.

Download full-text PDF

Source

Publication Analysis

Top Keywords

transplanted kidney
8
propofol fentanyl
8
fentanyl rocuronium
8
tof ratio
8
[sugammadex man
4
man transplanted
4
kidney case
4
case report]
4
report] report
4
report sugammadex
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!