Objective: Proportion of CIN II/III lesion on cervical biopsy among screen-positive women of age group < 40 years and ≥ 40 years undergoing screening for carcinoma cervix by Pap smear and visual inspection of cervix with acetic acid (VIA) was determined (both the tests were performed on same population). Difference in proportion of CIN II/III lesion among screen-positive women, between two age groups (for both methods) and between methods (for both age groups) was determined.
Result: In < 40 years age group, proportion of screen-positive women with CIN II/III lesion was similar for both cytology or VIA (12.95 vs. 9.8%). For ≥ 40 year age group, compared to cytology, VIA detected higher proportions of CIN II or III lesion (4.1 vs. 13.3%). Proportion of screen-positive women having CIN II/III lesion was higher in < 40 years compared to ≥ 40 year age group (12.95 vs. 4.1%) with cytology, while for VIA no difference was detected in between age groups (9.8 vs. 13.3%).
Conclusion: Cytological screening is less sensitive in women ≥ 40 years while VIA has a uniform sensitivity for both groups.
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http://dx.doi.org/10.1007/s00404-012-2228-3 | DOI Listing |
Clin Gastroenterol Hepatol
January 2025
Inflammatory Bowel Disease Center, Division of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville FL. Electronic address:
Description: The aim of this American Gastroenterological Association (AGA) Clinical Practice Update (CPU) is to provide best practice advice (BPA) statements for gastroenterologists and other health care providers who provide care to patients with inflammatory bowel disease (IBD). The focus is on IBD-specific screenings (excluding colorectal cancer screening, which is discussed separately) and vaccinations. We provide guidance to ensure that patients are up to date with the disease-specific cancer screenings, vaccinations, as well as advice for mental health and general wellbeing.
View Article and Find Full Text PDFAm J Gastroenterol
January 2025
University of Chicago Medicine, Inflammatory Bowel Disease Center.
Arthritis Care Res (Hoboken)
January 2025
Stanford University School of Medicine, Palo Alto, CA, USA.
Acta Obstet Gynecol Scand
January 2025
Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Introduction: Diagnostic work-up of older women with a positive cervical cancer screening test is often challenging due to incomplete visualization of the transformation zone. To reduce the risk of missing disease, a diagnostic cervical excision may be performed. However, little is known on treatment efficacy and post-treatment surveillance for older women.
View Article and Find Full Text PDFAm J Obstet Gynecol
December 2024
Women's Health Connecticut Lab, Rocky Hill, CT.
Noninvasive prenatal screening is a long-established and widely used methodology to screen pregnancies for the most common prenatal chromosomal aneuploidies. Since 2017, positive result reports have typically included a positive predictive value to assist informed clinical decision-making. Positive predictive value is calculated based on an assay's sensitivity and specificity for a particular condition, and for the purpose of noninvasive prenatal screening, the aneuploidy's prevalence by maternal age, sometimes further adjusted by gestational age, are included in the calculation.
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