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Oral transmission of L-type bovine spongiform encephalopathy in primate model. | LitMetric
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Oral transmission of L-type bovine spongiform encephalopathy in primate model.

Nadine Mestre-Francés Simon Nicot Sylvie Rouland Anne-Gaëlle Biacabe Isabelle Quadrio Armand Perret-Liaudet Thierry Baron Jean-Michel Verdier

Emerg Infect Dis

Institut National de la Santé et de la Recherche Médicale (INSERM) U710, Montpellier, France.

Published: January 2012

We report transmission of atypical L-type bovine spongiform encephalopathy to mouse lemurs after oral or intracerebral inoculation with infected bovine brain tissue. After neurologic symptoms appeared, transmissibility of the disease by both inoculation routes was confirmed by detection of disease-associated prion protein in samples of brain tissue.

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 Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310119PMC
http://dx.doi.org/10.3201/eid1801.111092DOI Listing

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