Background/aims: Laparoscopic cholecystectomy is the gold standard treatment for symptomatic gallstones. The goal of this study was to investigate the effect of cholecystectomy on alkaline reflux, histopathological changes in the gastric mucosa and H. pylori colonization.
Methodology: Eighty five patients who had undergone laparoscopic cholecystectomy were included in this trial (20 males; 65 females; 44.97 ± 11.22 years). All the patients had an upper gastrointestinal endoscopy before and 6 months after the surgery and biopsies in the antrum and corpus were taken to investigate the mucosal changes and assay for the presence of H. pylori.
Results: At 6 months post-surgery, the presence of bile in the fasting gastric fluid and an increase in the endoscopic gastritis findings were detected. While none of the patients had chemical gastritis prior to surgery, 7 patients were diagnosed with this condition after surgery. Intestinal metaplasia was detected in 6 patients prior to surgery and 20 patients after surgery. H. pylori was observed in 64 patients before surgery and 52 patients after surgery.
Conclusions: An increase in duodenogastric reflux, alkaline reflux gastritis and intestinal metaplasia, and a reduction in H. pylori colonization were observed to occur post-cholecystectomy.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.5754/hge11244 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Remote ischemic preconditioning on perioperative autonomic nervous system function and postoperative recovery in patients undergoing cholecystectomy.
Scand J Gastroenterol
January 2025
Department of Anesthesiology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Background: Cholecystectomy often disrupts autonomic balance, impacting recovery. Remote ischemic preconditioning (RIPC) may enhance ANS function and protect organs, but its role in cholecystectomy is unclear.
Methods: In this randomized controlled trial, 80 patients aged 45 to 65 years, scheduled for elective laparoscopic cholecystectomy, were randomly assigned to either the RIPC group or the control group.
Economics of emergency laparoscopic cholecystectomy at an Australian tertiary centre in the post COVID-19 era.
Am J Surg
December 2024
Upper GastroIntestinal Unit, Department of Surgery, St George Public Hospital, NSW Health, Australia; UNSW Department of Surgery, St George & Sutherland Clinical School, The University of New South Wales, Sydney, New South Wales, Australia.
Background: Laparoscopic cholecystectomy (LC) is a common operation performed worldwide. Indications include acute cholecystitis (AC), with a trend of increasing complexity post-COVID-19. We aim to evaluate the health expenditure on LC at an Australian tertiary centre.
View Article and Find Full Text PDFBiliary complications of surgical procedures: what the radiologist needs to know.
Abdom Radiol (NY)
December 2024
University of Kentucky, Lexington, USA.
Post-surgical biliary complications increase morbidity, mortality, and healthcare utilization. Early detection and management of biliary complications is thus of great clinical importance. Even though the overall risk for biliary complications is low after laparoscopic cholecystectomy, post-cholecystectomy biliary complications are frequently encountered in clinical practice as laparoscopic cholecystectomy is the most common surgical procedure performed in the United States.
View Article and Find Full Text PDFminimally invasive surgery is the surgery of the present and has become the "gold standard" for the most pathologies. The training of surgeons in minimally invasive techniques is mandatory required to be carried out during the residency program. In Romania, there is no national minimally invasive surgical training program, only universities and certain university hospitals are concerned with this aspect.
View Article and Find Full Text PDFComparative Assessment Between the Fundus-First Technique and Standard Laparoscopic Technique in Difficult Laparoscopic Cholecystectomy.
Cureus
November 2024
Department of General Surgery, Kalinga Institute of Medical Sciences, Bhubaneswar, IND.
Background: Laparoscopic cholecystectomy is a standard minimally invasive technique for the treatment in gallstone disease. In difficult laparoscopic cholecystectomies, bailout strategies have been developed of which the fundus-first technique is one. The present study aims to compare the outcomes of the fundus-first technique against the standard laparoscopic approach in managing difficult cholecystectomy cases by focusing on intraoperative factors such as bleeding, bile duct injury, operative time, and postoperative complications like biliary leakage.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!