Background And Purpose: The occurrence of PWD in neurodegenerative disease is very rare, and this is the first report of it being related to early-onset AD. We describe a patient with early-onset Alzheimer's disease (AD) who presented with pure word deafness (PWD).
Case Report: The patient had experienced PWD for 2 years, followed by other cognitive deficits suggestive of parietotemporal dysfunction. Brain imaging including (18)FDG-PET and [(11)C] PIB-PET supported the diagnosis of AD.
Conclusions: Our case highlights the clinical variability that characterizes early-onset AD.
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http://dx.doi.org/10.3988/jcn.2011.7.4.227 | DOI Listing |
Otolaryngol Head Neck Surg
January 2025
Department of Otolaryngology-Head and Neck Surgery, Columbia University Vagelos College of Physicians and Surgeons, NewYork-Presbyterian/Columbia University Irving Medical Center, New York, New York, USA.
Objective: Hearing loss (HL) is associated with depression, but existing datasets are limited by the type of data available for both hearing and mental health conditions. The purpose of this study is to determine if there is an association between HL and depressive disorders within a large bi-institutional electronic health record (EHR) system containing more granular diagnostic information.
Study Design: Cross-sectional epidemiologic study.
Laryngoscope
January 2025
Department of Otolaryngology, Walter Reed National Military Medical Center, Bethesda, Maryland, U.S.A.
Objectives: To investigate hearing aid utilization rates among populations with varying hearing aid insurance benefits.
Methods: A retrospective cohort study was performed. A total of 377 patients were included in the study after being identified through consecutive, hearing loss-related otology clinic visits.
Acta Otolaryngol
January 2025
Department of Otolaryngology - Head & Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA.
Background: There is conflicting literature regarding whether cochlear implants (CI) electrode array (EA) selection impacts audiologic outcomes.
Objective: To compare outcomes for the two EA designs, precurved and straight.
Methods: A systematic search of CINAHL, Cochrane Library, PubMed, and SCOPUS was conducted according to PRISMA guidelines.
Undersea Hyperb Med
January 2025
Department of Surgery, New York University Langone Health, New York, NY.
Objective: To determine the outcomes of patients receiving hyperbaric oxygen therapy for sudden sensorineural hearing loss and the impact of patient comorbidities on outcomes.
Study Design: Retrospective chart review.
Setting: Tertiary referral center.
Brain
January 2025
Department of Neurology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Acoustic-phonetic perception refers to the ability to perceive and discriminate between speech sounds. Acquired impairment of acoustic-phonetic perception is known historically as "pure word deafness" and typically follows bilateral lesions of the cortical auditory system. The extent to which this deficit occurs after unilateral left hemisphere damage and the critical left hemisphere areas involved are not well defined.
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